Ragab A H, Burger P, Badnitsky S, Krischer J, Van Eys J
J Neurooncol. 1986;3(4):341-2. doi: 10.1007/BF00165583.
Seventeen children with recurrent medulloblastoma and ependymoma received PCNU (100 mg/m2) in a Phase II trial. Response was evaluated by CAT scan. There were no responses. Administration of PCNU was associated with significant thrombocytopenia.
17名复发性髓母细胞瘤和室管膜瘤患儿在一项II期试验中接受了PCNU(100mg/m²)治疗。通过计算机断层扫描(CAT)评估反应。未出现反应。PCNU的使用与显著的血小板减少症相关。