穿越历史：胶质母细胞瘤手术的演变。

Cutting Through History: The Evolution of Glioblastoma Surgery.

机构信息

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON M5S 1A1, Canada.

Division of Neurosurgery, Department of Surgery, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.

出版信息

Curr Oncol. 2024 Oct 24;31(11):6568-6576. doi: 10.3390/curroncol31110485.

DOI:10.3390/curroncol31110485

PMID:39590116

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11592654/

Abstract

Despite significant advancements in neuro-oncology, management of glioblastoma remains a formidable challenge. Over the last century, the role and goals of surgery for patients with glioblastoma have evolved dramatically, with surgical intervention maintaining a central role in patient care. To understand the future role of surgery in the management of glioblastoma, we must review and appreciate the historical journey that has led us to this juncture. Here, we provide an overview of this evolution and speak about anticipated changes in the future. ""-Ernest Sachs, 1950.

摘要

尽管神经肿瘤学取得了重大进展，但胶质母细胞瘤的治疗仍然是一个巨大的挑战。在上个世纪，胶质母细胞瘤患者的手术角色和目标发生了巨大变化，手术干预在患者治疗中保持着核心地位。为了了解手术在胶质母细胞瘤治疗中的未来作用，我们必须回顾和欣赏使我们走到这一阶段的历史进程。在这里，我们概述了这一演变，并探讨了未来的预期变化。-恩斯特·萨克斯，1950 年。