Wang Tianyu, Duan Keran, Cai Xian, Chen Qi, Zu Liping, Liu Lingyan, Wu Xiaomin, Li Chenyu, Ma Fei
Department of Epidemiology and Statistics, School of Public Health, Tianjin Medical University, Tianjin 300070, China.
Department of clinical laboratory, Tianjin Medical University General Hospital, Tianjin 300052, China.
Curr Alzheimer Res. 2024;21(7):517-525. doi: 10.2174/0115672050347596241111112811.
The association between physical activity (PA) and cognitive function remains controversial, and the impact of gender on this association remains underexplored. Therefore, this study aimed to investigate the association between PA and cognitive function and to explore whether this association was modified by gender among older adults.
In 2016, a cluster sampling method was used to select community-dwelling older adults aged 65 and above. PA was assessed using the International Physical Activity Questionnaire-Short Form and classified as low, middle, and high. Cognitive function was assessed using the revised Chinese version of the Wechsler Adult Intelligence Scale. The multiple linear regression model was used to explore the association between PA and cognitive function and to assess whether this association differs by gender.
A total of 676 participants with a mean age of 73.63 ± 6.39 were included. The multiple linear regression analysis showed that higher PA was significantly statistically associated with higher Full Intelligence Quotient (FIQ), Performance Intelligence Quotient (PIQ), and verbal Intelligence Quotient (VIQ) scores (P<0.05). Among the WAIS-RC subtests, higher PA was significantly statistically associated with higher scores of the similarity subtest, picture completion subtest, and picture arrangement subtest (P<0.05). In the gender subgroup analysis, higher PA was significantly statistically associated with higher FIQ and PIQ scores (P<0.05), but no significant association was found with VIQ scores (P>0.05) in the male group, while in the female group, there was no significant statistical association between higher PA and FIQ, PIQ, or VIQ scores (P>0.05).
Higher PA was significantly statistically associated with better cognitive function (P<0.05). In the male group, PA was significantly statistically associated with cognitive function, whereas no comparable association was found in the female group.
体力活动（PA）与认知功能之间的关联仍存在争议，且性别对这种关联的影响尚未得到充分研究。因此，本研究旨在调查PA与认知功能之间的关联，并探讨在老年人中这种关联是否因性别而异。
2016年，采用整群抽样方法选取65岁及以上的社区居住老年人。使用国际体力活动问卷简表评估PA，并将其分为低、中、高三个等级。使用修订后的中文版韦氏成人智力量表评估认知功能。采用多元线性回归模型探讨PA与认知功能之间的关联，并评估这种关联是否因性别而异。
共纳入676名参与者，平均年龄为73.63±6.39岁。多元线性回归分析显示，较高的PA与较高的全智商（FIQ）、操作智商（PIQ）和言语智商（VIQ）得分显著相关（P<0.05）。在韦氏成人智力量表中国修订版（WAIS-RC）子测试中，较高的PA与相似性子测试、图片完成子测试和图片排列子测试的较高得分显著相关（P<0.05）。在性别亚组分析中，较高的PA与男性组的较高FIQ和PIQ得分显著相关（P<0.05），但与VIQ得分无显著关联（P>0.05），而在女性组中，较高的PA与FIQ、PIQ或VIQ得分之间无显著统计学关联（P>0.05）。
较高的PA与较好的认知功能显著相关（P<0.05）。在男性组中，PA与认知功能显著相关，而在女性组中未发现类似关联。
