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药物涂层球囊成功治疗冠状动脉穿孔:病例报告。

Successful management of coronary artery perforation with drug-coated balloon: a case report.

机构信息

Department of Emergency, Bayannaoer Hospital, No. 98 Wulan Buhe Road, Linhe District, Bayannaoer City, 015000, Inner Mongolia, China.

出版信息

BMC Cardiovasc Disord. 2024 Nov 26;24(1):680. doi: 10.1186/s12872-024-04309-9.

Abstract

BACKGROUND

Coronary artery perforation (CAP) is a rare but serious complication of Percutaneous coronary intervention (PCI) with significant morbidity and mortality. Traditional management involves the use of covered stents, yet alternative interventions may be necessary. To report a unique case of CAP managed effectively with a drug-coated balloon, highlighting a novel application of this technology in emergency PCI.

CASE PRESENTATION

A 73-year-old male with a history of chronic angina, hypertension, and diabetes underwent PCI for severe stenosis in the mid-left anterior descending (LAD) artery. During the procedure, a large vessel CAP occurred. Immediate management included hemodynamic stabilization via fluid resuscitation and dopamine administration, followed by the deployment of drug-coated balloons instead of the conventional covered stent to seal the perforation. The intervention successfully sealed the perforation with restoration of thrombolysis in myocardial infarction 3 flow, and the patient remained hemodynamically stable. Follow-up over six months showed no adverse cardiovascular events and normal cardiac function was maintained.

CONCLUSIONS

This case demonstrates the potential of drug-coated balloons as a feasible alternative to covered stents in managing CAP, particularly in large vessel perforations. Further research is warranted to assess the long-term safety and efficacy of this approach.

摘要

背景

冠状动脉穿孔 (CAP) 是经皮冠状动脉介入治疗 (PCI) 的一种罕见但严重的并发症,具有较高的发病率和死亡率。传统的治疗方法包括使用覆膜支架,但可能需要其他介入治疗。本文报告了一例成功使用药物涂层球囊治疗 CAP 的独特病例,强调了该技术在急诊 PCI 中的新应用。

病例介绍

一名 73 岁男性,有慢性心绞痛、高血压和糖尿病病史,因严重左前降支(LAD)中段狭窄而行 PCI。手术过程中发生了大血管 CAP。立即采用液体复苏和多巴胺给药进行血流动力学稳定,随后使用药物涂层球囊而非传统的覆膜支架来封堵穿孔。介入治疗成功地封堵了穿孔,心肌梗死溶栓治疗血流达到 3 级,患者血流动力学稳定。随访 6 个月以上无不良心血管事件,心功能正常。

结论

本病例表明药物涂层球囊在治疗 CAP,特别是大血管穿孔方面,是覆膜支架的一种可行替代方法。需要进一步研究以评估这种方法的长期安全性和疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d09d/11590260/905af212f513/12872_2024_4309_Fig1_HTML.jpg

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