Komaki K, Sakamoto G, Sugano H, Kasumi F, Watanabe S, Fukami A, Nishi M
Gan No Rinsho. 1986 Jan;Suppl:238-47.
To evaluate the accuracy in diagnosing breast lesions by frozen sections, 657 consecutive diagnostic biopsies seen during 1982 were reviewed. Of 559 lesions considered benign at frozen sections, 558 were also benign in paraffin sections, the remaining one being a papillary carcinoma (i.e. 1/559 or 0.2% false negative). All 78 cases diagnosed as malignant in frozen sections were also malignant in paraffin sections (i.e. 0% false positive). Of the 20 doubtful cases, in frozen sections, 15 showed a papillary lesions; 7 of them were malignant in paraffin sections and the rest 13 benign. It is concluded that the frozen sections are usefull in the diagnoses of mammary disorders except for those cases with papillary tumors.
为评估冰冻切片诊断乳腺病变的准确性,我们回顾了1982年期间连续进行的657例诊断性活检。在冰冻切片中被认为是良性的559个病变中,558个在石蜡切片中也是良性的,其余1个是乳头状癌(即假阴性率为1/559或0.2%)。所有在冰冻切片中诊断为恶性的78例病例在石蜡切片中也均为恶性(即假阳性率为0%)。在冰冻切片中有20例可疑病例,其中15例显示为乳头状病变;其中7例在石蜡切片中为恶性,其余13例为良性。结论是,除乳头状肿瘤病例外,冰冻切片在乳腺疾病的诊断中是有用的。