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经椎间孔注射类固醇治疗腰骶部疼痛时灌注指数变化与镇痛效果的相关性:一项前瞻性观察研究

Correlation of perfusion index change and analgesic efficacy in transforaminal steroid injection for lumbosacral pain, a prospective observational study.

作者信息

Gatorwala Heley, Bangera Ananda

机构信息

Department of Anaesthesiology and Critical Care, K. S. Hegde Medical Academy, Mangaluru, Karnataka, India.

出版信息

Saudi J Anaesth. 2024 Oct-Dec;18(4):509-515. doi: 10.4103/sja.sja_244_24. Epub 2024 Oct 2.

DOI:10.4103/sja.sja_244_24
PMID:39600461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11587962/
Abstract

BACKGROUND AND AIMS

Low back pain is a common problem and a major burden to society. Transforaminal epidural steroid injection is one of the most effective treatment modalities for back pain. We aim to objectively quantify pain relief of lumbosacral radicular pain post transforaminal steroid injection by correlating perfusion index (PI), reflecting real-time peripheral blood flow change at the site of monitoring, controlled by sympathetic system with Numerical rate score (NRS) and SLRT improvement.

MATERIAL AND METHODS

A prospective observational study, conducted at K.S Hegde Medical Academy, Mangaluru, from June 2021 to June 2022 as a time-bound study. After IEC clearance (IEC certificate number) for the procedure and study, patients undergoing transforaminal epidural steroid injection for lumbosacral radicular pain were enrolled, excluding those meeting the exclusion criteria. PI change and NRS score improvement were noted at 0, 5, 10, 15, and 30 minutes along with pre and post-procedure SLRT. Results were analyzed.

RESULTS

A total of 40 patients were analyzed. PI change at 30 minutes was 2.113 from a baseline of 0.217. Median NRS of 5, improved to 0 and the mean SLRT of 45.17 to 61.45 at the end of 30 minutes. All changes are statistically significant with (<0.01). correlation between the PI change with NRS is mild (-0.312).

CONCLUSION

PI change ratio shows an overall improvement in pain levels objectively, in a non-invasive, easy, and reliable way. Simultaneous improvement in both NRS and SLRT is clinically significant but cannot predict a correlated quantitative measure of pain relief.

摘要

背景与目的

腰痛是一个常见问题,给社会带来重大负担。经椎间孔硬膜外类固醇注射是治疗背痛最有效的方法之一。我们旨在通过将灌注指数(PI)与数字评分量表(NRS)评分及直腿抬高试验(SLRT)改善情况相关联,客观量化经椎间孔类固醇注射后腰骶部神经根性疼痛的疼痛缓解情况。PI反映了受交感神经系统控制的监测部位实时外周血流变化。

材料与方法

这是一项前瞻性观察性研究,于2021年6月至2022年6月在芒格洛尔的K.S赫格德医学院进行,为有时间限制的研究。在该操作和研究获得伦理委员会批准(伦理委员会证书编号)后,纳入接受经椎间孔硬膜外类固醇注射治疗腰骶部神经根性疼痛的患者,排除符合排除标准的患者。在0、5、10、15和30分钟时记录PI变化和NRS评分改善情况,以及操作前后的SLRT。对结果进行分析。

结果

共分析了40例患者。30分钟时PI变化为2.113,基线为0.217。NRS中位数从5改善到0,30分钟末SLRT平均从45.17改善到61.45。所有变化均具有统计学意义(<0.01)。PI变化与NRS之间的相关性较弱(-0.312)。

结论

PI变化率以非侵入性、简便且可靠的方式客观显示了疼痛水平的总体改善。NRS和SLRT同时改善具有临床意义,但无法预测疼痛缓解的相关定量指标情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e12/11587962/aba42adf0a3f/SJA-18-509-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e12/11587962/aba42adf0a3f/SJA-18-509-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e12/11587962/aba42adf0a3f/SJA-18-509-g001.jpg

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