低骨骼肌质量：口腔癌患者游离前臂皮瓣重建术后手术并发症的强预测因素。
Low Skeletal Muscle Mass: A Strong Predictive Factor for Surgical Complications After Free Forearm Flap Reconstruction in Oral Cancer Patients.
作者信息
Ansari E, Minulina N Carrillo, van Beers M A, van Es R J J, Dieleman F J, Rosenberg A J W P, Janssen L M, Braunius W W, Van Cann E M, de Bree R
机构信息
Department of Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
Department of Oral and Maxillofacial Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
出版信息
Head Neck. 2025 Apr;47(4):1135-1141. doi: 10.1002/hed.28014. Epub 2024 Nov 27.
BACKGROUND
Low skeletal muscle mass (SMM) is a predictive factor for complications in patients undergoing major head and neck cancer surgery. This study aims to identify the predictive value of low SMM for postoperative complications in patients who underwent free forearm flap (FAFF) reconstructions after oral cancer resections.
METHODS
A retrospective study was performed with all patients who underwent FFAF between 2003 and 2020 for an oral cavity reconstruction after cancer ablation. Free flap related, any postoperative complications and hospital stay were investigated.
RESULTS
Low SMM was associated with an increased risk of free flap associated complications (OR 2.14; 95% CI 1.02-4.39, p = 0.029). Low SMM was associated with severe complications (Clavien-Dindo ≥ III) (OR 1.46; 95% CI 1.20-2.09, p = 0.02).
CONCLUSIONS
Low SMM is a strong predictive factor for free flap related surgical complications in patients undergoing FAFF reconstruction after resection of oral cancer.
背景
低骨骼肌质量（SMM）是接受重大头颈癌手术患者并发症的预测因素。本研究旨在确定低SMM对口腔癌切除术后接受游离前臂皮瓣（FAFF）重建患者术后并发症的预测价值。
方法
对2003年至2020年间所有接受FAFF进行癌症切除术后口腔重建的患者进行回顾性研究。调查游离皮瓣相关情况、任何术后并发症及住院时间。
结果
低SMM与游离皮瓣相关并发症风险增加相关（比值比2.14；95%置信区间1.02 - 4.39，p = 0.029）。低SMM与严重并发症（Clavien-Dindo≥III级）相关（比值比1.46；95%置信区间1.20 - 2.09，p = 0.02）。
结论
低SMM是口腔癌切除术后接受FAFF重建患者游离皮瓣相关手术并发症的有力预测因素。
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