Bernheim J, Rathaus V, Rathaus M, Bernheim J
Nephrologie. 1986;7(1):28-30.
Among the complications associated with primary hyperparathyroidism, anemia has not been extensively studied. In order to assess the frequency of this anemia we make a retrospective study of the medical records of 62 patients with a primary hyperparathyroidism. In 40 of the 62 hyperparathyroidic patients the diagnosis was surgically proven (group 1) and in 22, typical laboratory changes were found (group 2). In all these cases no other causes of anemia, except hyperparathyroidism, could be found. The 2 groups were similar concerning age and sex. A normochromicnormocytic anemia was present in 11 patients in group 1 (24,5%) and in 7 in group 2 (31, 8%). This anemia was corrected after a successfull parathyroidectomy (parathyroid adenoma in all the operated cases). Anemia was correlated with neither Ca and P blood levels nor C1/P ratio. A significant inverse correlation was found between age and hemoglobin in anemic hyperparathyroidic patients. The etiopathogeny of this findings is discussed.
在与原发性甲状旁腺功能亢进相关的并发症中，贫血尚未得到广泛研究。为了评估这种贫血的发生率，我们对62例原发性甲状旁腺功能亢进患者的病历进行了回顾性研究。62例甲状旁腺功能亢进患者中，40例经手术证实诊断（第1组），22例发现典型的实验室变化（第2组）。在所有这些病例中，除甲状旁腺功能亢进外，未发现其他贫血原因。两组在年龄和性别方面相似。第1组有11例患者（24.5%）存在正细胞正色素性贫血，第2组有7例（31.8%）。在成功进行甲状旁腺切除术后（所有手术病例均为甲状旁腺腺瘤），这种贫血得到纠正。贫血与血钙、血磷水平及氯/磷比值均无相关性。在贫血的甲状旁腺功能亢进患者中，年龄与血红蛋白之间存在显著的负相关。本文讨论了这一发现的病因。
