Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada; Servicio de Cardiología, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria 12 de Octubre, Madrid, Spain; Consorcio de Investigación Biomédica en Red-Cardiovascular, Madrid, Spain.
Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.
JACC Cardiovasc Interv. 2024 Nov 25;17(22):2575-2595. doi: 10.1016/j.jcin.2024.07.032.
Conduction disturbances (CDs) are common after transcatheter aortic valve replacement. Continuous improvements in preprocedural planification, implant techniques, and device design have markedly reduced periprocedural complications. However, CDs rate remains in the double-digit range. Because CDs after TAVR are associated with poorer outcomes, seeking a reduction in their occurrence is paramount. Several nonmodifiable and modifiable factors are associated with an increased risk of CDs. Previous right bundle branch block has been shown to have a strong association with pacemaker implant after TAVR. Among the modifiable factors, a lower implantation depth seems to be associated with a higher risk of CDs, and several implant strategies aiming to obtain a higher implant depth have shown promising results. This literature review provides a detailed description of updated evidence about the epidemiology, impact, and preventive and management strategies of CDs after TAVR. Also, based on these updated data, a fast-track protocol CDs management is proposed.
经导管主动脉瓣置换术后常发生传导障碍(CDs)。术前规划、植入技术和器械设计的不断改进,明显降低了围手术期并发症的发生率。然而,CDs 的发生率仍在两位数范围内。由于 TAVR 后的 CDs 与预后较差相关,因此降低其发生率至关重要。一些不可变和可改变的因素与 CDs 的发生风险增加有关。先前的右束支传导阻滞已被证明与 TAVR 后的起搏器植入有很强的相关性。在可改变的因素中,较低的植入深度似乎与 CDs 的风险增加有关,并且几种旨在获得更高植入深度的植入策略已显示出有前景的结果。本文献综述详细描述了 TAVR 后 CDs 的流行病学、影响以及预防和管理策略的最新证据。此外,基于这些更新的数据,提出了一种快速通道 CD 管理方案。