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在美学区域,使用脱细胞真皮基质的前庭沟治疗与结缔组织移植物行即刻种植体植入治疗有缺陷的拔牙窝的随机对照临床试验。

Immediate implant placement in compromised extraction sockets using vestibular socket therapy with acellular dermal matrix versus connective tissue grafts in the esthetic zone: a randomized controlled clinical trial.

机构信息

Oral Medicine, Periodontology, Oral Diagnosis and Radiology Department, Faculty of Dentistry, Tanta University, Tanta, Egypt.

Private Practice, Alexandria, Egypt.

出版信息

Clin Oral Investig. 2024 Nov 28;28(12):664. doi: 10.1007/s00784-024-06065-8.

DOI:10.1007/s00784-024-06065-8
PMID:39604639
Abstract

BACKGROUND

Immediate implant placement (IIP) in compromised extraction sockets poses significant challenges in maintaining the contour and level of mucosal tissues. This study compares the efficacy of vestibular socket therapy (VST) combined with acellular dermal matrix (ADM) versus connective tissue grafts (CTG) in IIP within the esthetic zone.

METHODS

Twenty participants requiring extraction in the maxillary esthetic zone were randomized into two groups: ADM and CTG (n = 10 each). Both groups underwent VST with bone grafting and dental implant placement. Clinical outcomes were evaluated at baseline, 6 months, and 12 months, measuring soft-tissue level and thicknesses, and the radiographic facial alveolar bone thicknesses and height.

RESULTS

Both groups resulted in statistically significant increase in coronal mucosal thickness, facial bone height and thickness over time. CTG showed statistically significant increase at apical mucosal thickness over time, whereas the ADM group had a significantly higher facial bone height after 12 months. No significant differences were observed between groups in mucosal thickness and level at any time point and both groups achieved 100% implant survival.

CONCLUSION

ADM and CTG are both effective for soft tissue augmentation and hard-tissue maintenance in IIP within compromised extraction sockets after 12 months. CTG may offer advantages in apical mucosal thickness, while ADM was associated with greater bone height.

CLINICAL RELEVANCE

Both ADM and CTG effectively enhance soft tissue and maintain hard-tissue levels, with CTG providing better apical mucosal thickness and ADM resulting in greater facial bone height after 12 months. These insights help clinicians to customize treatment plans based on individual goals and patient needs.

摘要

背景

在有缺陷的拔牙窝中立即植入(IIP)会对维持粘膜组织的轮廓和水平带来重大挑战。本研究比较了前庭沟治疗(VST)联合脱细胞真皮基质(ADM)与结缔组织移植物(CTG)在美学区 IIP 中的疗效。

方法

20 名需要在上颌美学区拔牙的参与者被随机分为两组:ADM 组和 CTG 组(每组 10 名)。两组均行 VST 联合骨移植和牙种植体植入。在基线、6 个月和 12 个月时评估临床结果,测量软组织水平和厚度,以及影像学面牙槽骨厚度和高度。

结果

两组的冠状粘膜厚度、面骨高度和厚度均随时间呈统计学显著增加。CTG 在根尖粘膜厚度上随时间呈统计学显著增加,而 ADM 组在 12 个月后面骨高度显著增加。两组在任何时间点的粘膜厚度和水平均无显著差异,两组的种植体存活率均为 100%。

结论

ADM 和 CTG 在 12 个月后,在有缺陷的拔牙窝中立即植入时,对于软组织增加和硬组织维持都是有效的。CTG 可能在根尖粘膜厚度方面具有优势,而 ADM 与更大的骨高度相关。

临床相关性

ADM 和 CTG 均可有效增强软组织并维持硬组织水平,CTG 可提供更好的根尖粘膜厚度,而 ADM 在 12 个月后可导致更大的面骨高度。这些发现有助于临床医生根据个人目标和患者需求定制治疗计划。

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