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即刻种植同期应用脱细胞真皮基质或结缔组织移植:一项随机对照的临床容量研究。

Immediate Implant Placement in Conjunction with Acellular Dermal Matrix or Connective Tissue Graft: A Randomized Controlled Clinical Volumetric Study.

出版信息

Int J Periodontics Restorative Dent. 2022 May-Jun;42(3):381-390. doi: 10.11607/prd.5632.

DOI:10.11607/prd.5632
PMID:35472115
Abstract

Connective tissue grafts have become a standard for compensating horizontal volume loss in immediate implant placement. The use of new biomaterials like acellular matrices may avoid the need to harvest autogenous grafts, yielding less postoperative morbidity. This randomized comparative study evaluated the clinical outcomes following extraction and immediate implant placement in conjunction with anorganic bovine bone mineral (ABBM) and the use of a porcine acellular dermal matrix (ADM) vs an autogenous connective tissue graft (CTG) in the anterior maxilla. Twenty patients (11 men, 9 women) with a mean age of 48.9 years (range: 21 to 72 years) were included in the study and randomly assigned to either the test (ADM) or control (CTG) group. They underwent tooth extraction and immediate implant placement together with ABBM for socket grafting and either ADM or CTG for soft tissue augmentation. Twelve months after implant placement, the cases were evaluated clinically and volumetrically. All implants achieved osseointegration and were restored. The average horizontal change of the ridge dimension at 1 year postsurgery was -0.55 ± 0.32 mm for the ADM group and -0.60 ± 0.49 mm for the CTG group. Patients of the ADM group reported significantly less postoperative pain. Using xenografts for hard and soft tissue augmentation in conjunction with immediate implant placement showed no difference in the volume change in comparison to an autogenous soft tissue graft, and showed significantly less postoperative morbidity.

摘要

结缔组织移植物已成为补偿即刻种植体植入中水平体积损失的标准方法。使用脱细胞基质等新型生物材料可能避免需要采集自体移植物,从而减少术后发病率。本随机对照研究评估了在前上颌骨中,在拔牙和即刻种植体植入的同时使用无机牛骨矿物质(ABBM)和使用猪脱细胞真皮基质(ADM)与自体结缔组织移植物(CTG)的临床结果。20 名患者(11 名男性,9 名女性),平均年龄为 48.9 岁(范围:21 至 72 岁),被纳入研究并随机分为试验(ADM)组或对照(CTG)组。他们接受了拔牙和即刻种植体植入,同时使用 ABBM 进行牙槽骨移植,并用 ADM 或 CTG 进行软组织增量。植入物放置 12 个月后,对病例进行临床和体积评估。所有植入物均实现了骨整合并得到了修复。ADM 组的颊侧骨嵴在术后 1 年的平均水平变化为 -0.55 ± 0.32mm,CTG 组为 -0.60 ± 0.49mm。ADM 组患者术后疼痛明显较轻。使用异种移植物进行硬组织和软组织增量与即刻种植体植入相结合,与自体软组织移植物相比,在体积变化方面没有差异,且术后发病率明显较低。

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