Nguyen Thanh N, Xiong Yunyun, Li Shuya, Abdalkader Mohamad, Chen Hui-Sheng
Department of Neurology, Radiology, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, USA.
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing.
Curr Opin Neurol. 2025 Feb 1;38(1):3-9. doi: 10.1097/WCO.0000000000001337. Epub 2024 Nov 28.
Advances in intravenous thrombolysis and endovascular thrombectomy have significantly reduced disability and improved outcomes associated with acute ischemic stroke.
An expansion of indications for reperfusion therapies in select groups of patients to permit treatment in an extended time window, with large ischemic core, and with simplified imaging protocols have enabled a broader group of patients access to disability-sparing therapy. Cerebroprotection has had renewed development in the era of acute reperfusion.
In this review, we highlight recent developments in stroke reperfusion research and related questions that are under study or remain unanswered.
静脉溶栓和血管内血栓切除术的进展显著降低了急性缺血性卒中相关的残疾率并改善了预后。
在特定患者群体中扩大再灌注治疗的适应症，以允许在更长的时间窗内、针对大面积缺血核心以及采用简化成像方案进行治疗，使得更多患者能够获得减少残疾的治疗。在急性再灌注时代，脑保护研究有了新的进展。
在本综述中，我们重点介绍了卒中再灌注研究的最新进展以及正在研究或尚未解答的相关问题。
