Department of General and Colorectal Surgery, Russells Hall Hospital, Dudley Group NHS Foundation Trust, Dudley, UK.
Department of General and Colorectal Surgery, Queen's Hospital Burton, University Hospital of Derby and Burton NHS Foundation Trust, Derby, UK.
Int J Colorectal Dis. 2024 Nov 28;39(1):190. doi: 10.1007/s00384-024-04752-2.
Colostomy formation as part of the Hartmann's procedure is often performed during emergency surgery as a damage limitation measure where attempts at bowel anastomosis and continuity are contraindicated. Hartmann's reversal (HR) remains challenging and can be attempted through open surgery and various minimally invasive techniques (laparoscopic and robotic platforms). We aimed to analyse outcomes of conventional multi-port laparoscopy (CL) versus single-incision approach (SILS) in patients undergoing HR.
A comprehensive online search of various databases was conducted in accordance with PRISMA guidelines including Medline, PubMed, Embase, and Cochrane. Comparative studies of patients undergoing CL and SILS for HR were included. Analysed primary outcomes were total operative time and mortality rate. Secondary outcomes included post-operative complications, length of hospital stay, risk of visceral injury intra-operatively, and re-operation rate. Combined overall effect sizes were calculated using the random-effects model, and the Newcastle-Ottawa Scale (NOS) was used to assess bias.
Two observational studies matching our inclusion criteria with a total of 160 patients (SILS 100 vs. CL 60) were included. Statistical difference was observed for one outcome measure: operative duration (MD - 44.79 CI - 65.54- - 24.04, P < 0.0001). No significant difference was seen in mortality rate (OR 1.66 CI 0.17-16.39, P = 0.66), overall post-operative complications (OR 0.60 CI 0.28-1.32, P = 0.20), length of stay (MD - 0.22 CI - 4.25-3.82, P = 0.92), Clavien-Dindo III + complications (OR 0.61 CI 0.15-2.53, P = 0.50), risk of visceral injury (OR 1.59 CI 0.30-8.31, P = 0.58), and re-operation rates (OR 0.73 CI 0.08-6.76, P = 0.78).
Accounting for study limitations, the SILS procedure seems to be quicker with non-inferior outcomes compared with the conventional multi-port approach. This may lead to better patient satisfaction and cosmesis and potentially reduce the risk of future incisional hernia occurrence. However, well-designed, randomised studies are needed to draw more robust conclusions and recommendations.
Hartmann 手术中结肠造口术的形成通常是作为一种限制损害的措施在紧急手术中进行的,因为肠吻合术和连续性是禁忌的。Hartmann 逆转(HR)仍然具有挑战性,可以通过开放手术和各种微创技术(腹腔镜和机器人平台)进行尝试。我们旨在分析接受 HR 的患者常规多孔腹腔镜(CL)与单切口方法(SILS)的结果。
根据 PRISMA 指南,对各种数据库(包括 Medline、PubMed、Embase 和 Cochrane)进行了全面的在线搜索。纳入了接受 CL 和 SILS 进行 HR 的患者的比较研究。分析的主要结局是总手术时间和死亡率。次要结局包括术后并发症、住院时间、术中内脏损伤风险和再次手术率。使用随机效应模型计算了组合的总效应大小,并使用纽卡斯尔-渥太华量表(NOS)评估偏倚。
有两项符合我们纳入标准的观察性研究,共纳入 160 名患者(SILS 100 例与 CL 60 例)。一个结局指标存在统计学差异:手术时间(MD-44.79 CI-65.54-24.04,P<0.0001)。死亡率(OR 1.66 CI 0.17-16.39,P=0.66)、总术后并发症(OR 0.60 CI 0.28-1.32,P=0.20)、住院时间(MD-0.22 CI-4.25-3.82,P=0.92)、Clavien-Dindo III+并发症(OR 0.61 CI 0.15-2.53,P=0.50)、内脏损伤风险(OR 1.59 CI 0.30-8.31,P=0.58)和再次手术率(OR 0.73 CI 0.08-6.76,P=0.78)均无显著差异。
考虑到研究的局限性,SILS 手术似乎比传统的多孔方法更快,且具有非劣效的结果。这可能会提高患者满意度和美观度,并降低未来切口疝发生的风险。然而,需要进行精心设计的随机研究以得出更稳健的结论和建议。