Suppr超能文献

终末期颞下颌关节退行性关节病患者接受关节镜下高级清创术是否与生活质量改善和疼痛减轻相关?

Is Advanced Arthroscopic Debridement in Patients With End-Stage Temporomandibular Joint Degenerative Joint Disease Associated With Improved Quality of Life and Pain Reduction?

作者信息

Cheung Johnson, Aronovich Sharon, Troost Jonathan P, Hakim Mohamed

机构信息

Former TMJ Surgery Fellow, Department of Oral and Maxillofacial Surgery, University of Michigan, Ann Arbor, MI.

Faculty Member and Clinical Associate Professor, Department of Oral and Maxillofacial Surgery, University of Michigan, Ann Arbor, MI.

出版信息

J Oral Maxillofac Surg. 2025 Feb;83(2):138-147. doi: 10.1016/j.joms.2024.11.003. Epub 2024 Nov 9.

Abstract

BACKGROUND

Temporomandibular joint (TMJ) advanced arthroscopic debridement (level II arthroscopy) is a minimally invasive procedure involving microsurgical debridement of degenerated tissues with aid of a fiber-optic camera. Its use for treating intra-articular pain and dysfunction (IPD) in advanced TMJ degenerative disease remains debated.

PURPOSE

The primary purpose was to evaluate if level II arthroscopy was associated with improvement in pain and quality of life in subjects with advanced TMJ degenerative disease, and to identify clinical factors that influence outcomes.

STUDY DESIGN, SETTING, SAMPLE: This was a retrospective cohort study conducted on subjects who presented to the University of Michigan oral and maxillofacial surgery clinic between November 2020 and July 2023 who required arthroscopy for IPD. Inclusion criteria were unilateral or bilateral IPD, Wilkes V disease, arthroscopically verified disc perforation, and 3-month minimum follow-up. Subjects with level I/III arthroscopy or with Wilkes I-IV disease were excluded.

COVARIATES

The covariates included demographics (age, sex), preoperative variables (body mass index, allergies, environmental sensitivities, condylar degeneration, systemic arthropathy, serology, prior arthrocentesis, preoperative jaw functional limitation scale (JFLS) and pain), and operative variables (synovitis, chondromalacia, adhesions, laterality, debridement, and injections).

MAIN OUTCOME VARIABLES

Primary outcomes were changes in quality of life and pain measured via the JFLS and visual analog pain scale, respectively, at minimum 3-month post-arthroscopy.

ANALYSES

Linear regression analyzed JFLS with covariates, and linear-mixed effects models adjusted for nonindependent pain from bilateral TMJ sides. Paired t-tests compared mean JFLS and pain scores with significance set at P < .05.

RESULTS

A total of 240 subjects were screened and 40 subjects completed the study with mean age of 49.33 (±13.62) years, 95% subjects were female, and median follow-up of 7 months (interquartile range 6 to 8). Mean JFLS decreased from 73.3 (±34.94) to 43.8 (±35.35) postoperatively (P < .0001). Mean pain scores decreased from 60.0 (±21.2) to 38.0 (±28.5) postoperatively (P < .0001). Environmental sensitivity was the only covariate significantly associated with higher postoperative JFLS (P = .002). Three subjects (7.5%) required total arthroplasty post-level II arthroscopy.

CONCLUSION AND RELEVANCE

Advanced arthroscopic debridement (level II arthroscopy) is associated with reduced pain and improved quality of life in subjects with Wilkes V degenerative joint disease.

摘要

背景

颞下颌关节(TMJ)高级关节镜清创术(二级关节镜检查)是一种微创手术,借助光纤摄像头对退变组织进行显微清创。其用于治疗晚期TMJ退行性疾病的关节内疼痛和功能障碍(IPD)仍存在争议。

目的

主要目的是评估二级关节镜检查是否与晚期TMJ退行性疾病患者的疼痛改善和生活质量提高相关,并确定影响治疗结果的临床因素。

研究设计、地点、样本:这是一项回顾性队列研究,研究对象为2020年11月至2023年7月期间到密歇根大学口腔颌面外科诊所就诊、因IPD需要进行关节镜检查的患者。纳入标准为单侧或双侧IPD、威尔克斯V级疾病、关节镜证实的盘穿孔以及至少3个月的随访。排除接受一级/三级关节镜检查或患有威尔克斯I-IV级疾病的患者。

协变量

协变量包括人口统计学特征(年龄、性别)、术前变量(体重指数、过敏、环境敏感性、髁突退变、全身关节病、血清学、既往关节穿刺、术前颌功能受限量表(JFLS)和疼痛)以及手术变量(滑膜炎、软骨软化、粘连、侧别、清创和注射)。

主要结局变量

主要结局分别是关节镜检查后至少3个月通过JFLS和视觉模拟疼痛量表测量的生活质量和疼痛变化。

分析

线性回归分析JFLS与协变量的关系,线性混合效应模型对双侧TMJ侧的非独立疼痛进行校正。配对t检验比较JFLS和疼痛评分的均值,显著性设定为P <.05。

结果

共筛选出240名受试者,40名受试者完成研究,平均年龄为49.33(±13.62)岁,95%为女性,中位随访时间为7个月(四分位间距为6至8个月)。术后JFLS均值从73.3(±34.94)降至43.8(±35.35)(P <.0001)。术后疼痛评分均值从60.0(±21.2)降至38.0(±28.5)(P <.0001)。环境敏感性是唯一与术后较高JFLS显著相关的协变量(P =.002)。三名受试者(7.5%)在二级关节镜检查后需要进行全关节置换术。

结论及意义

高级关节镜清创术(二级关节镜检查)与威尔克斯V级退行性关节疾病患者疼痛减轻和生活质量改善相关。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验