Department of Respiratory Medicine, Royal Brompton Hospital, London, UK.
Department of Respiratory Medicine, Royal Brompton Hospital, London, UK; Division of Surgery and Interventional Science, Institute of Sport, Exercise and Health (ISEH), University College London, London, UK.
Immunol Allergy Clin North Am. 2025 Feb;45(1):39-52. doi: 10.1016/j.iac.2024.08.008. Epub 2024 Oct 20.
Large airway collapse on expiration is an increasingly recognized cause of airway centric symptoms. The 2 primary conditions are tracheobronchomalacia and excessive dynamic airway collapse, the latter a common comorbidity in those with underlying lung disease. The exertional dyspnea associated with these conditions is complex and exercise intolerance is a key clinical feature, despite the fact that the precise relationship is not fully understood. Forced expiratory maneuvers during supine bronchoscopy or imaging studies are used to evaluate these conditions. However, it may be relevant to characterize large airway function during occasions when patients present their symptoms.
大气道在呼气时塌陷是气道中心性症状日益被认识到的一个原因。2 种主要情况是气管支气管软化和过度动态性气道塌陷,后者是基础肺部疾病患者的常见合并症。这些情况相关的运动性呼吸困难较为复杂,运动耐量差是一个关键的临床特征,尽管确切的关系尚未完全了解。在仰卧位支气管镜检查或影像学研究期间进行用力呼气动作来评估这些情况。然而,在患者出现症状时,对大气道功能进行特征描述可能是相关的。