Mank R, Zessin G, Fahr F
Pharmazie. 1986 Jan;41(1):42-4.
The authors report with the example of the model drug, caffeine, on the preparation and investigation of matrix tablets on the basis of acrylates. The release values obtained were analysed by the equations of Higuchi and also Noyes-Whitney. It was demonstrated, that the polymer composition and the drug content in the tablets have an influence on the release of the drug.
作者以模型药物咖啡因为例，报告了基于丙烯酸酯类的骨架片的制备及研究情况。通过Higuchi方程以及Noyes - Whitney方程对所获得的释放值进行了分析。结果表明，片剂中的聚合物组成及药物含量对药物释放有影响。
