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集合不足干预措施的有效性:一项使用AS20评估临床结局和健康相关生活质量的观察性研究。

Effectiveness of interventions for convergence insufficiency: an observational study evaluating clinical outcomes and health-related quality of life using AS20.

作者信息

Jong Joel Lee Zher, Saleem Zainab, Simmons Joshua, Rhodes Martin, Choi Jessy

机构信息

School of Medicine and Population Health, University of Sheffield, Sheffield, UK.

Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield Teaching Hospital NHS Foundation Trust, Sheffield, UK.

出版信息

Eye (Lond). 2025 Apr;39(5):918-924. doi: 10.1038/s41433-024-03510-6. Epub 2024 Nov 28.

Abstract

BACKGROUND

Convergence insufficiency (CI) is a common condition that can impair visual performance and comfort during close visual work. This observational study evaluated the effectiveness of interventions on clinical outcomes and health-related quality-of-life using the Adult Strabismus-20 (AS20) questionnaire in patients with CI.

METHODS

Data was extracted from a database collected at first consultation from 2015 to 2022. Demographics, interventions and outcomes of 75 patients with CI (mean age 47.2 ± 24.7 years) were analysed.

RESULTS

Orthoptic exercises were prescribed to 58% of patients, 28% received prisms and 9% received no treatment. At the latest follow-up review, 24% were recommended to continue exercises, 24% had prisms, 1 underwent bimedial resection and 1 had treatment with Botulinum Toxin A (BTXA). The median follow-up was 5.0 (0-55) months, 100% were discharged with 25% following failure-to-attend and 11% died. At the latest follow-up, the attendance failure rate was higher for exercises (36%) than for prisms (10%). Both near-prism cover test and near-point of convergence improved from a median of 12 (95% CI 10-14) prism dioptres (PD) to 8.5 (95% CI 6-12) PD, and 17.5 (95%CI 15-20) cm to 10.0 (95%CI 8.3-12.0) cm respectively (p < 0.05). Near-prism fusion range also improved from 10(95%CI 8-14) PD to 16(95% CI 12-20) PD (p < 0.05). The median AS20 score at presentation were 100/100 (30-100) and 47.5/100 (0-100), and post-intervention were 100/100 (75-100) and 70/100 (12.5-97.5) for psychosocial and functional components, respectively.

CONCLUSION

This cohort offers valuable insights into the real-life clinical management of CI in a tertiary adult strabismus centre. However, the study also found that long-term compliance with treatment is intrinsically challenging, emphasising the importance of disease education.

摘要

背景

集合不足(CI)是一种常见病症,可在近距离视觉工作期间损害视觉表现和舒适度。这项观察性研究使用成人斜视 - 20(AS20)问卷评估了干预措施对CI患者临床结局和健康相关生活质量的有效性。

方法

数据从2015年至2022年首次咨询时收集的数据库中提取。分析了75例CI患者(平均年龄47.2±24.7岁)的人口统计学、干预措施和结局。

结果

58%的患者接受了视轴矫正训练,28%接受了棱镜治疗,9%未接受治疗。在最近一次随访复查时,24%的患者被建议继续训练,24%佩戴棱镜,1例接受双眼内直肌切除术,1例接受A型肉毒杆菌毒素(BTXA)治疗。中位随访时间为5.0(0 - 55)个月,100%的患者出院,其中25%未按时就诊,11%死亡。在最近一次随访时,训练组的未按时就诊率(36%)高于棱镜组(10%)。近棱镜遮盖试验和集合近点分别从中位值12(95%CI 10 - 14)棱镜度(PD)改善至8.5(95%CI 6 - 12)PD,以及从17.5(95%CI 15 - 20)cm改善至10.0(95%CI 8.3 - 12.0)cm(p < 0.05)。近棱镜融合范围也从10(95%CI 8 - 14)PD改善至16(95%CI 12 - 20)PD(p < 0.05)。就诊时AS20评分的中位值在心理社会和功能成分方面分别为100/100(30 - 100)和47.5/100(0 - 100),干预后分别为100/100(75 - 100)和70/100(12.5 - 97.5)。

结论

该队列研究为三级成人斜视中心CI的实际临床管理提供了有价值的见解。然而,研究还发现长期治疗依从性本质上具有挑战性,强调了疾病教育的重要性。

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本文引用的文献

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J Pediatr Ophthalmol Strabismus. 2023 Mar-Apr;60(2):108-113. doi: 10.3928/01913913-20220324-02. Epub 2022 May 25.
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The efficacy of bupivacaine for the treatment of strabismus.布比卡因治疗斜视的疗效。
Strabismus. 2022 Mar;30(1):42-47. doi: 10.1080/09273972.2021.2022714. Epub 2022 Feb 11.
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Interventions for convergence insufficiency: a network meta-analysis.集合不足的干预措施:网络荟萃分析。
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