Experimental Orthopaedics and Trauma Surgery, Department of Orthopaedics, Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Medical Magnesium GmbH, Philipsstraße 8, 52068, Aachen, Germany.
J Orthop Surg Res. 2024 Nov 28;19(1):802. doi: 10.1186/s13018-024-05208-7.
Titanium plantar plates have proven successful in the fixation of the first tarsometatarsal arthrodesis (TMT). However, a second surgery is typically needed for implant removal, and potential adverse effects, carried by the conventional implantations, are not uncommon. The purpose of this study was to determine whether a novel magnesium-based plantar plate system provides similar fusion stability to a titanium-based plantar plate system under various loading conditions.
Six matched-pair human cadaveric specimens underwent TMT fusions using either a magnesium plantar plate system prototype or a titanium plantar plate system. Specimens were cyclically loaded with a force ranging from 5 N to 50 N for 5,000 cycles, and displacement was recorded. Axial stiffness (N/mm) was calculated from load-displacement curves. Each specimen was loaded to failure at a rate of 5 mm/min, and the ultimate load was recorded.
No significant difference was found in the vertical displacement between Ti group and Mg group after 100 cycles (2.4 ± 1.0 mm vs. 1.3 ± 1.4 mm, p = 0.196), 500 cycles (3.3 ± 1.3 mm vs. 1.7 ± 1.7 mm, p = 0.142), 1,000 cycles (3.7 ± 1.5 mm vs. 1.9 ± 1.9 mm, p = 0.128), 2,500 cycles (4.2 ± 1.7 mm vs. 2.3 ± 2.2 mm, p = 0.172) and 5,000 cycles (4.5 ± 1.8 mm vs. 2.3 ± 3.3 mm, p = 0.125), Additionally, no significant differences were observed in initial stiffness (53.1 ± 19.2 N/mm vs. 82.2 ± 53.9 N/mm, p = 0.257), final stiffness (90.6 ± 48.9 N/mm vs. 120.0 ± 48.3 N/mm, p = 0.319), or maximum load-to-failure (259.8 ± 98.2 N vs. 323.9 ± 134.9 N, p = 0.369).
Based on the performed biomechanical testing, the magnesium plantar plate system provides mechanical stability equivalent to the titanium plantar plate system in fixation for the first TMT joint fusion.
钛制跖骨板在第一跖跗关节融合术（TMT）的固定中已被证明是成功的。然而，通常需要进行第二次手术以取出植入物，并且传统植入物带来的潜在不良反应并不少见。本研究旨在确定新型镁基跖骨板系统在各种加载条件下是否能提供与钛基跖骨板系统相似的融合稳定性。
六对配对的人尸体标本分别采用镁制跖骨板系统原型或钛制跖骨板系统进行 TMT 融合。标本在 5N 至 50N 的力下循环加载 5000 次，记录位移。从载荷-位移曲线计算轴向刚度（N/mm）。以 5mm/min 的速率对每个标本进行加载直至失效，并记录最大载荷。
在 100 次循环后（2.4 ± 1.0mm 与 1.3 ± 1.4mm，p=0.196）、500 次循环后（3.3 ± 1.3mm 与 1.7 ± 1.7mm，p=0.142）、1000 次循环后（3.7 ± 1.5mm 与 1.9 ± 1.9mm，p=0.128）、2500 次循环后（4.2 ± 1.7mm 与 2.3 ± 2.2mm，p=0.172）和 5000 次循环后（4.5 ± 1.8mm 与 2.3 ± 3.3mm，p=0.125），钛组和镁组之间的垂直位移没有显著差异。此外，初始刚度（53.1 ± 19.2N/mm 与 82.2 ± 53.9N/mm，p=0.257）、最终刚度（90.6 ± 48.9N/mm 与 120.0 ± 48.3N/mm，p=0.319）或最大失效载荷（259.8 ± 98.2N 与 323.9 ± 134.9N，p=0.369）也没有显著差异。
根据进行的生物力学测试，镁制跖骨板系统在固定第一跖跗关节融合时提供的机械稳定性与钛制跖骨板系统相当。
