Dept. of Stomatology, Hainan Medical University, Haikou 571199, China.
Dept. of Pathology, The First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2024 Dec 1;42(6):822-827. doi: 10.7518/hxkq.2024.2024098.
GLI1-altered mesenchymal tumors are a relatively rare type of mesenchymal tumor that is common in the head and neck. It is a newly added tumor type in the World Health Organization Tumor Classification of Head and Neck (5th edition). This article reports a case ofGLI1alteredmesenchymal tumor occurring at the left tongue and reviews the relevant literature to summarize the pathological morphological characteristics, immunophenotype, molecular changes, clinical manifestations, and prognosis of the disease.
GLI1 改变型间叶肿瘤是一种相对罕见的间叶肿瘤,常见于头颈部。它是世界卫生组织头颈部肿瘤分类(第五版)中新增加的肿瘤类型。本文报告了一例发生于左侧舌部的 GLI1 改变型间叶肿瘤,并复习相关文献,总结该病的病理形态学特征、免疫表型、分子改变、临床表现及预后。