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肉毒杆菌毒素和电生理干预改善乳房内置假体术后:一项临床试验研究。

Botulinum Toxin and Electrophysiological Intervention Improve Post-Surgical Breast Entdoprosthetics: A Clinical Trial Study.

机构信息

Samarkand State Medical University, Samarkand, Uzbekistan.

St. Petersburg Research Institute of Emergency Medicine, St. Petersburg, Russia.

出版信息

Asian Pac J Cancer Prev. 2024 Nov 1;25(11):3817-3821. doi: 10.31557/APJCP.2024.25.11.3817.

Abstract

INTRODUCTION

The majority of plastic surgeon specialists note a distinct tendency to increase the number of breasts endoprosthetic surgeries with silicone implants in the Republic of Uzbekistan - the number of such surgeries now reaches 3-4 thousand annually. Breast replacement for aesthetic purposes is widespread throughout the world and has been rapidly spreading in Uzbekistan in recent years. Due to surgical endoprosthetics of mammary gland tissue with silicone implants, both in the early and late postoperative periods, quite often the patient's body experiences typical postoperative pain, which, if subclinical, requires constant dynamic monitoring and preventive rehabilitation procedures. Rehabilitation measures are a prerequisite for a successfully performed aesthetic surgery to enlarge the mammary glands.

MATERIALS AND METHODS

To address the effectiveness of intramuscular botulinum toxin A and the INDIBA electromagnetic field electrophysiology we used, a prospective randomized trial was designed to evaluate the effectiveness of patient-reported postoperative pain and pain reduction in these settings.

RESULTS

The results of the conducted research allow us to conclude that the course of electrophysiological influence by INDIBA preparation, conducted in the first week, daily, i.e. 7 procedures after aesthetic breast endoprosthetics, significantly increases the efficiency of anesthetic effect of botulinum toxin type A drug administration 14 days before the intervention.

DISCUSSION

These studies results allow us to conclude that a course of electrophysiological treatment with INDIBA, conducted in the first week after aesthetic breast endoprosthetics, significantly increases the effectiveness of the analgesic effect of botulinum toxin.

CONCLUSION

Thus, the given results are convincing in terms of the fact that the proposed complex of rehabilitation measures after aesthetic endoprosthetics of mammary glands in the form of parenteral intramuscular administration of botulinum toxin preparation and a course of electrophysiological influence by electromagnetic field has a statistically significant pathogenetically-based pronounced and prolonged analgesic effect in the postoperative period.

摘要

简介

大多数整形外科专家注意到,在乌兹别克斯坦共和国,乳房内假体硅胶植入手术的数量明显增加 - 目前此类手术的数量每年达到 3-4 千例。出于美容目的的乳房置换术在全球范围内广泛开展,近年来在乌兹别克斯坦迅速普及。由于乳房组织的外科假体硅胶植入,无论是在早期还是晚期术后,患者的身体经常会经历典型的术后疼痛,如果是亚临床的,则需要持续的动态监测和预防康复措施。康复措施是成功进行乳房增大美容手术的前提。

材料和方法

为了评估肌肉内注射肉毒杆菌毒素 A 和 INDIBA 电磁场电生理学的有效性,我们设计了一项前瞻性随机试验,以评估这些情况下患者报告的术后疼痛和疼痛减轻的效果。

结果

进行的研究结果使我们能够得出结论,即 INDIBA 制剂进行的电生理影响疗程,在第一周内每天进行,即在美容乳房内假体术后的第 7 天进行,显著提高了肉毒杆菌毒素 A 药物治疗的麻醉效果 14 天前的干预。

讨论

这些研究结果使我们能够得出结论,即在美容乳房内假体术后的第一周内进行 INDIBA 电生理治疗疗程,显著提高了肉毒杆菌毒素的镇痛效果。

结论

因此,从事实上来看,所提出的乳房美容假体后康复措施的综合方案,包括肌肉内注射肉毒杆菌毒素制剂和电磁场的电生理影响疗程,在术后具有统计学意义上的基于病理的明显且持久的镇痛效果。

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