Savvala Natalia, Amico Mailis, Joumaa Saaddedine, Jaussent Audrey, Silvestri Marta, Lefebvre Patrick, Khamajeet Arvin, Picot Marie Christine, Galtier Florence, Nocca David
Digestive Surgery Department, Montpellier University Hospital, Montpellier, France.
Clinical Research and Epidemiology Unit, CHU Montpellier, Univ Montpellier, Montpellier, France.
Surg Obes Relat Dis. 2025 Mar;21(3):311-318. doi: 10.1016/j.soard.2024.10.019. Epub 2024 Oct 29.
Nissen sleeve gastrectomy is a new bariatric procedure based on the combination of 2 well-known surgical techniques (vertical sleeve gastrectomy and Nissen fundoplication). It was conceived as a means to prevent the major drawback of the sleeve gastrectomy (SG), the gastroesophageal reflux disease (GERD), while preserving the advantages of SG in terms of weight loss, and remission of obesity-related comorbidities.
The objectives of this study are to present the long-term (5 years) follow-up results on weight loss, evolution of GERD and other comorbidities, and the complication rate of the Nissen sleeve gastrectomy.
Montpellier University Hospital, France.
This is a prospective analysis of patients who underwent Nissen sleeve gastrectomy as a first-line bariatric procedure between January 2018 and February 2019. A subgroup analysis of patients with no further surgery during follow-up was also performed.
A total of 144 patients underwent Nissen sleeve gastrectomy: After adjusting for exclusion criteria, 133 patients comprised the initial study population, 81.9% of whom had complete follow-up for weight and GERD clinical symptom outcomes at 5 years. The mean total weight loss (TWL%) was 22 (±12.3)% and the mean excess weight loss percentage (EWL%) was 59.4% (±34.2)%. Of the 63 patients with preoperative clinical symptoms of GERD, we observed an 85.5% 5-year clinical remission rate; however, only 25 patients had a gastroscopy at 5 years. The cumulative short- and long-term reoperation rate was 8.1% and the mortality rate was zero.
The Nissen sleeve gastrectomy achieves a satisfactory long-term TWL% and a significant improvement in comorbidities, particularly regarding the incidence of GERD. The rate of complications requiring surgical reoperation is low.
nissen袖状胃切除术是一种新的减肥手术，它基于两种著名的外科技术（垂直袖状胃切除术和nissen胃底折叠术）的结合。它被认为是一种预防袖状胃切除术（SG）主要缺点——胃食管反流病（GERD）的方法，同时保留SG在减肥以及缓解肥胖相关合并症方面的优势。
本研究的目的是呈现nissen袖状胃切除术在减肥、GERD及其他合并症的演变以及并发症发生率方面的长期（5年）随访结果。
法国蒙彼利埃大学医院。
这是一项对2018年1月至2019年2月期间接受nissen袖状胃切除术作为一线减肥手术患者的前瞻性分析。还对随访期间未进行进一步手术的患者进行了亚组分析。
共有144例患者接受了nissen袖状胃切除术：在根据排除标准进行调整后，133例患者构成初始研究人群，其中81.9%的患者在5年时对体重和GERD临床症状结局进行了完整随访。平均总体重减轻（TWL%）为22（±12.3）%，平均超重减轻百分比（EWL%）为59.4%（±34.2）%。在63例术前有GERD临床症状的患者中，我们观察到5年临床缓解率为85.5%；然而，只有25例患者在5年时进行了胃镜检查。累积短期和长期再次手术率为8.1%，死亡率为零。
nissen袖状胃切除术实现了令人满意的长期TWL%，并在合并症方面有显著改善，尤其是在GERD发生率方面。需要手术再次干预的并发症发生率较低。
