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中国女性直接植入式和组织扩张器即刻乳房重建:手术并发症与患者报告结局的比较

Direct-to-implant and tissue expander-based immediate breast reconstruction in Chinese women: A comparison of surgical complications and patient-reported outcomes.

作者信息

Zhang Yuwei, Du Fengzhou, Zeng Ang, Yu Nanze, Zhang Hailin, Long Xiao, Wang Xiaojun

机构信息

Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing 100730, PR China.

Department of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing 100730, PR China.

出版信息

J Plast Reconstr Aesthet Surg. 2025 Jan;100:131-143. doi: 10.1016/j.bjps.2024.09.053. Epub 2024 Sep 17.

Abstract

BACKGROUND

Direct-to-implant (DTI) breast reconstruction restores patient body image immediately after mastectomy but may increase postoperative complications compared to tissue expander (TE)-based breast reconstruction. Few studies have compared the surgical complications and patient-reported outcomes (PROs) of DTI and TE breast reconstructions in Asian women.

METHOD

This study compared postoperative complications and PROs between DTI and TE breast reconstruction in Chinese women and explores the risk factors of postoperative complications and the influencing factors of PROs. A retrospective chart review of patients undergoing immediate breast reconstruction between 2008 and 2022 was conducted, and BREAST-Q questionnaires of the breast reconstruction module were distributed to eligible patients. Multivariate regression models were used to explore risk factors for postoperative complications and factors that influence BREAST-Q scores.

RESULTS

DTI was associated with lower rates of major complications and implant loss but had no significant influence on patient satisfaction or quality of life. Age and axillary lymph node dissection were important complication risk factors for both DTI and TE. The application of acellular dermal matrix significantly increased the risk of seroma or hematoma. In the DTI group, capsular contracture significantly reduced patient satisfaction with breast scores.

CONCLUSION

DTI dual-plane breast reconstruction does not increase complication rates in appropriately selected Chinese patients. In DTI patients, the management of capsular contracture is crucial for improving patient satisfaction.

摘要

背景

直接植入式(DTI)乳房重建可在乳房切除术后立即恢复患者的身体形象,但与基于组织扩张器(TE)的乳房重建相比,可能会增加术后并发症。很少有研究比较亚洲女性DTI和TE乳房重建的手术并发症及患者报告结局(PROs)。

方法

本研究比较了中国女性DTI和TE乳房重建术后的并发症及PROs,并探讨了术后并发症的危险因素和PROs的影响因素。对2008年至2022年间接受即刻乳房重建的患者进行回顾性病历审查,并向符合条件的患者发放乳房重建模块的BREAST-Q问卷。采用多变量回归模型探讨术后并发症的危险因素及影响BREAST-Q评分的因素。

结果

DTI与较低的主要并发症发生率和植入物丢失率相关,但对患者满意度或生活质量无显著影响。年龄和腋窝淋巴结清扫是DTI和TE重要的并发症危险因素。脱细胞真皮基质的应用显著增加了血清肿或血肿的风险。在DTI组中,包膜挛缩显著降低了患者对乳房评分的满意度。

结论

对于适当选择的中国患者,DTI双平面乳房重建不会增加并发症发生率。在DTI患者中,包膜挛缩的处理对提高患者满意度至关重要。

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