Tiozon Rhowell N, Lenaerts Bert, Kor Sakshi, Demont Matty, Fernie Alisdair R, Sreenivasulu Nese
Consumer-Driven Grain Quality and Nutrition Center, Rice Breeding and Innovation Department, International Rice Research Institute, Los Baños 4030, Philippines; Max-Planck-Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam-Golm 14476, Germany.
Sustainable Impact through Rice-Based Systems Department, International Rice Research Institute, Los Baños 4030, Philippines.
Trends Plant Sci. 2025 Jun;30(6):603-614. doi: 10.1016/j.tplants.2024.11.003. Epub 2024 Nov 29.
The prevalence of type 2 diabetes is rising worldwide, particularly in Asia, where rice is a dietary staple. Hence, it is essential to consume low glycemic index (GI) food. Here, we review the potential of low GI and high resistant starch (RS) of rice to mitigate diabetes risk. Progress has been made in lowering the GI of rice without compromising yield and grain quality through marker-assisted breeding techniques. To enhance RS content, mutation breeding and genome editing were used. Deployment of these new varieties in global food systems remains critical through policy initiatives such as 'Seeds without Borders' and the widespread deregulation of genome editing plants that can expedite the wider adoption of low-GI and high-RS rice.
2型糖尿病在全球范围内呈上升趋势,尤其是在以大米为主食的亚洲地区。因此,食用低血糖指数(GI)食物至关重要。在此,我们综述了大米的低GI和高抗性淀粉(RS)在降低糖尿病风险方面的潜力。通过标记辅助育种技术,在不影响产量和谷物品质的前提下降低大米的GI方面已取得进展。为提高RS含量,采用了诱变育种和基因组编辑技术。通过“无国界种子”等政策举措以及对基因组编辑植物的广泛解禁,将这些新品种推广到全球粮食系统中仍然至关重要,这可以加快低GI和高RS大米的更广泛应用。