Pandey Gita Sadaula, Pathak Chet Raj, Thapa Sunil, Sadaula Amir, Manandhar Prajwol, Abdelbaset Abdelbaset Eweda, Qiu Yongjin, Kwak Mackenzie L, Hayashi Naoki, Nonaka Nariaki, Nakao Ryo
Laboratory of Parasitology, Graduate School of Infectious Diseases, Faculty of Veterinary Medicine, Hokkaido University, Japan; National Cattle Research Program, Nepal Agricultural Research Council, Rampur, Chitwan, Nepal.
Agriculture and Forestry University, Rampur, Chitwan, Nepal.
Parasitol Int. 2025 Jun;106:103003. doi: 10.1016/j.parint.2024.103003. Epub 2024 Nov 30.
Tick-borne pathogens (TBPs) in dogs are a major global health concern, with their zoonotic importance often being neglected in developing countries due to a lack of surveillance. This study aimed to highlight the incidence of six important TBPs belonging to the genera Babesia, Theileria, Hepatozoon, Anaplasma, Ehrlichia, and Rickettsia in a total of 230 community dogs from two sites: Lumbini and the Kathmandu Valley, of Nepal. A total of 75 (32.6 %) dogs were found to be infected with at least one TBP, with 11 (4.7 %) being co-infected with more than one TBP. The detection rates of TBPs were 13.9 % (n = 32) for Ehrlichia canis, 9.1 % (n = 21) for Anaplasma platys, 8.6 % (n = 20) for Babesia vogeli, and 6.5 % (n = 15) for Babesia gibsoni. None of the samples were positive for Theileria, Hepatozoon, or Rickettsia. There was a significant association between A. platys and E. canis infections, respectively, with the locations from which the samples were collected. Infections of TBPs in community dogs might be the source of infection for pet dogs or even humans in shared habitats. Further studies are needed to determine the prevalence and diversity of TBPs in dogs in other regions of Nepal. As some of these parasites are zoonotic, concerted efforts are required to raise awareness of, and control efforts for, these tick-borne pathogens.
犬类蜱传病原体（TBPs）是全球主要的健康问题，由于缺乏监测，其在发展中国家的人畜共患病重要性常常被忽视。本研究旨在强调尼泊尔蓝毗尼和加德满都谷地两个地点的230只社区犬中，属于巴贝斯虫属、泰勒虫属、肝簇虫属、无形体属、埃立克体属和立克次体属的六种重要TBPs的感染率。总共发现75只（32.6%）犬至少感染一种TBP，其中11只（4.7%）同时感染多种TBP。犬埃立克体的TBP检出率为13.9%（n = 32），血小板无形体为9.1%（n = 21），伯氏巴贝斯虫为8.6%（n = 20），吉氏巴贝斯虫为6.5%（n = 15）。所有样本中泰勒虫、肝簇虫或立克次体均为阴性。血小板无形体和犬埃立克体感染分别与样本采集地点之间存在显著关联。社区犬中的TBPs感染可能是共享栖息地中宠物犬甚至人类的感染源。需要进一步研究以确定尼泊尔其他地区犬类中TBPs的流行情况和多样性。由于其中一些寄生虫是人畜共患的，因此需要共同努力提高对这些蜱传病原体的认识并加强防控措施。
