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肾移植受者宫颈癌筛查率低的悖论

The Paradox of Poor Cervical Cancer Screening Uptake for Kidney Transplant Recipients.

作者信息

Sharif Adnan

机构信息

Department of Nephrology and Transplantation, University Hospitals Birmingham, Queen Elizabeth Hospital, Birmingham, United Kingdom.

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.

出版信息

Cancer Epidemiol Biomarkers Prev. 2024 Dec 2;33(12):1544-1546. doi: 10.1158/1055-9965.EPI-24-1033.

Abstract

Kidney transplant recipients have an increased risk for developing and dying from cervical cancer compared with the general population due to their immunosuppressed state. As one of the cancers most amenable to an effective screening program, encouraging eligible women after transplantation to adhere to screening is critically important. Therefore, the observation that kidney transplant recipients may have a lower uptake of cervical cancer screening compared with the general population is concerning. The reasons for this should be studied so that any barriers can be identified and overcome. Kidney transplant recipients and recipients of other solid organ allografts must be encouraged and supported to adhere to recommended screening programs to mitigate the morbidity and mortality of posttransplantation cancer. See related article by Hsu et al., p. 1678.

摘要

与普通人群相比,肾移植受者由于处于免疫抑制状态,患宫颈癌及因宫颈癌死亡的风险增加。作为最适合有效筛查项目的癌症之一,鼓励移植后符合条件的女性坚持筛查至关重要。因此,肾移植受者宫颈癌筛查率可能低于普通人群这一现象令人担忧。应研究其原因,以便识别并克服任何障碍。必须鼓励并支持肾移植受者及其他实体器官同种异体移植受者坚持推荐的筛查项目,以降低移植后癌症的发病率和死亡率。见许等人的相关文章,第1678页。

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