沙特阿拉伯使用剩余抗生素自我药疗的知识与态度：一项横断面研究。

Knowledge and Attitude of self-medication with leftover antibiotics in Saudi Arabia: A cross-sectional study.

作者信息

Al-Mehmadi Bader, Alsubaie Saad, Al-Morikhi Omar, Alqahtani Fawaz, Almutairi Waad, Al-Mutairi Maryam, Alotaibi Mohammed, Alenazi Saud, Alanazi Khalid

机构信息

Assistant Professor of Medicine, Rheumatology Consultant, Department of Internal Medicine, College of Medicine, Majmaah University, Al-Majmaah, 11952, Saudi Arabia.

College of Medicine, Majmaah University, Al-Majmaah, Saudi Arabia, Al-Majmaah, Saudi Arabia.

出版信息

F1000Res. 2024 Oct 18;12:304. doi: 10.12688/f1000research.130364.2. eCollection 2023.

DOI:10.12688/f1000research.130364.2

PMID:39618514

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11607477/

Abstract

BACKGROUND

Antimicrobial resistance is increasing at an alarming rate. The use of antibiotics without a prescription by a patient or other family members and their inappropriate storage have caused serious health issues as it would lead to antibiotic resistance and exposure to the risk of harmful adverse effects unnecessarily. Therefore, the study aimed to evaluate the current behaviour of antibiotic usage, storage, re-usage and misuse among the residents of Saudi Arabia.

METHODS

This is a cross-sectional study. Our target study population was the residents of Saudi Arabia. Data were collected by an online questionnaire and analysed by SPSS.

RESULTS

A total of 738 participants answered the online questionnaire from all ages, genders, nationalities, and socioeconomic backgrounds residing in different regions across the Kingdom of Saudi Arabia. 76.42% knew that an antibiotic is a chemical substance used to treat infections. The participants were questioned about when they started using antibiotics, to which 95.66% (n=706) responded after consulting a physician, 3.25% (n=24) said when they felt ill for any reason, and 1.08% (n=8) replied after first attempting herbal medicine. A total of 147 participants admitted that they store excess pills of antibiotics after being prescribed for an infection and reuse them later on for symptoms like sore throat and fever.

CONCLUSIONS

The results indicated that nearly half of the participants used leftover antibiotics. Participants having children in their homes significantly reuse antibiotics. However, one-third of the participants didn't complete the antibiotics course. A large portion of the population, regardless of age, level of education, or professional background, have continued to store leftover antibiotics after an infection treatment and reuse them once they think they need them for new symptoms. This advice further revises the current measures to fill those gaps and reduce this habit.

摘要

背景

抗菌药物耐药性正以惊人的速度增长。患者或其他家庭成员无处方使用抗生素以及抗生素储存不当已引发严重的健康问题，因为这会导致抗生素耐药性，并使人不必要地面临有害副作用的风险。因此，本研究旨在评估沙特阿拉伯居民目前抗生素使用、储存、重复使用和滥用的行为。

方法

这是一项横断面研究。我们的目标研究人群是沙特阿拉伯居民。通过在线问卷收集数据，并使用SPSS进行分析。

结果

共有738名来自沙特阿拉伯王国不同地区、不同年龄、性别、国籍和社会经济背景的参与者回答了在线问卷。76.42%的人知道抗生素是用于治疗感染的化学物质。参与者被问及何时开始使用抗生素，其中95.66%（n = 706）回答是在咨询医生后使用，3.25%（n = 24）表示在因任何原因感到不适时使用，1.08%（n = 8）回答是在首次尝试草药后使用。共有147名参与者承认，他们在因感染而被开了抗生素后会储存多余的药片，之后再将其用于治疗喉咙痛和发烧等症状。

结论

结果表明，近一半的参与者使用过剩余抗生素。家中有孩子的参与者显著更倾向于重复使用抗生素。然而，三分之一的参与者没有完成抗生素疗程。很大一部分人群，无论年龄、教育程度或职业背景如何，在感染治疗后仍继续储存剩余抗生素，并在认为新症状需要时再次使用。本建议进一步修订了当前措施，以填补这些空白并减少这种习惯。