Features Associated With Mycoplasma genitalium Infection.

Background Sexually transmitted infections (STIs) are commonly encountered in the emergency department (ED) in the United States. Limited data exist on the prevalence and risk factors for . , specifically within the ED. We describe the epidemiological and laboratory findings associated with  infection at the Mayo Clinic, the whole institution, and specifically in the ED. Methods We examined Mayo Clinic Enterprise data for encounters occurring between October 29, 2014, and September 23, 2023, in patients 12-120 years of age who had research authorization present and had testing for , and . Results Among 332,619 encounters,  testing occurred in 1.7% (n=5,572) of encounters, in which a positive  test occurred in 1.8% (n=103) of those tested. Since 2020, there has been an increasing trend for  testing in the ED in the United States, yet testing for  occurred in <1% of those being tested for other STIs in the ED.  coinfection in the ED with gonorrhea, chlamydia, or trichomonas occurred <1% of the time for all. Factors significant for infection were non-White race (OR 2.33 95% CI (1.50-3.37)), age 45-101 years (vs. 25-35 years) (0.16 (0.05-0.42)), age 36-44 (vs. 25-35 years) (0.47 (0.21-0.94)), married/life partner (vs. divorced, separated, widowed, or unknown) (0.27 (0.11-0.72)), being tested in the ED (versus inpatient and outpatient) and infection with  species (3.19 (1.10-9.86)); p<0.04 for all. Conclusion  is infrequently tested in the ED, yet those tested in the ED had a high association with a positive infection. We identified other risk factors for  infection, including non-White race, age, marital status, and infection with  species.