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血浆置换作为缺血性中风的一种治疗方法:一例罕见的获得性血栓性血小板减少性紫癜病例

Plasmapheresis as an Ischaemic Stroke Treatment: A Rare Case of Acquired Thrombotic Thrombocytopenic Purpura.

作者信息

Barreto Francisco, Nóbrega Sofia, Fernandes Rui, Carvalhinha Carolina I, Faria Teresa

机构信息

Internal Medicine, Hospital Central do Funchal, Funchal, PRT.

出版信息

Cureus. 2024 Oct 31;16(10):e72762. doi: 10.7759/cureus.72762. eCollection 2024 Oct.

Abstract

Acquired thrombotic thrombocytopenic purpura (acquired TTP) is a rare clinical syndrome caused by a decreased ADAMST13 activity, leading to systemic microvascular thrombotic events, with high mortality rates when the diagnosis and treatment are delayed. The authors report an acquired TTP in a patient with cerebrovascular disease. The aim is to emphasize the importance of considering atypical acquired TTP clinical presentations in order to optimize diagnostic and treatment approaches, minimize possible sequels, and improve the prognosis.

摘要

获得性血栓性血小板减少性紫癜(获得性TTP)是一种罕见的临床综合征,由ADAMST13活性降低引起,导致全身微血管血栓形成事件,诊断和治疗延迟时死亡率很高。作者报告了一例患有脑血管疾病的患者发生获得性TTP。目的是强调考虑非典型获得性TTP临床表现的重要性,以便优化诊断和治疗方法,尽量减少可能的后遗症,并改善预后。

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