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成人免疫球蛋白A血管炎肾病

Immunoglobulin A Vasculitis Nephritis in an Adult.

作者信息

Gopalakrishnan Sritheja, Chandrasekaran Nirmala Devi, Kumar Janardanan, Jayakumar Chandni, Jayaprakash Varadharajan

机构信息

General Medicine, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, Sri Ramaswamy Memorial (SRM) Institute of Science and Technology, Chengalpattu, IND.

Nephrology, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, Sri Ramaswamy Memorial (SRM) Institute of Science and Technology, Chengalpattu, IND.

出版信息

Cureus. 2024 Oct 29;16(10):e72672. doi: 10.7759/cureus.72672. eCollection 2024 Oct.

DOI:10.7759/cureus.72672
PMID:39618651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11605163/
Abstract

Immunoglobulin A vasculitis (IgAV; initially known as Henoch-Schönlein purpura) is a form of vasculitis involving the small blood vessels of the gastrointestinal tract, skin, joints, and kidney, presenting as a multisystem disorder. A 21-year-old gentleman presented with joint pain, skin rash, abdominal pain, and proteinuria. Biopsies performed from the skin and kidney were both consistent with IgA deposition. The patient was treated with a short course of low-dose steroids because of the involvement of multiple organ systems. His symptoms abated, proteinuria resolved, and steroids were stopped after four weeks. He remains in complete remission at the time of the last follow-up, 12 months after the initial presentation.

摘要

免疫球蛋白A血管炎（IgAV；最初称为过敏性紫癜）是一种累及胃肠道、皮肤、关节和肾脏小血管的血管炎，表现为多系统疾病。一名21岁男性出现关节疼痛、皮疹、腹痛和蛋白尿。皮肤和肾脏活检均与IgA沉积一致。由于多器官系统受累，该患者接受了短疗程低剂量类固醇治疗。他的症状减轻，蛋白尿消失，四周后停用类固醇。在初次就诊12个月后的最后一次随访时，他仍处于完全缓解状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/72a17a65b701/cureus-0016-00000072672-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/ddcae862b0b1/cureus-0016-00000072672-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/62cfafd0cf26/cureus-0016-00000072672-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/c6d8b2cd5da7/cureus-0016-00000072672-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/ea9725c77998/cureus-0016-00000072672-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/72a17a65b701/cureus-0016-00000072672-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/ddcae862b0b1/cureus-0016-00000072672-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/62cfafd0cf26/cureus-0016-00000072672-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/c6d8b2cd5da7/cureus-0016-00000072672-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/ea9725c77998/cureus-0016-00000072672-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02f8/11605163/72a17a65b701/cureus-0016-00000072672-i05.jpg

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本文引用的文献

1
Long-Term Outcomes in IgA Nephropathy.IgA 肾病的长期预后。
Clin J Am Soc Nephrol. 2023 Jun 1;18(6):727-738. doi: 10.2215/CJN.0000000000000135. Epub 2023 Apr 13.
2
Diagnostic and Management Strategies of IgA Vasculitis Nephritis/Henoch-Schönlein Purpura Nephritis in Pediatric Patients: Current Perspectives.儿童IgA血管炎肾炎/过敏性紫癜肾炎的诊断与管理策略：当前观点
Pediatric Health Med Ther. 2023 Mar 7;14:89-98. doi: 10.2147/PHMT.S379862. eCollection 2023.
3
Immunoglobulin a (IgA) Vasculitis in the Elderly.老年人免疫球蛋白A（IgA）血管炎
Cureus. 2023 Jan 31;15(1):e34422. doi: 10.7759/cureus.34422. eCollection 2023 Jan.
4
Viral Infections May Be Associated with Henoch-Schönlein Purpura.病毒感染可能与过敏性紫癜有关。
J Clin Med. 2023 Jan 16;12(2):697. doi: 10.3390/jcm12020697.
5
IgA vasculitis update: Epidemiology, pathogenesis, and biomarkers.IgA 血管炎最新研究进展：流行病学、发病机制和生物标志物。
Front Immunol. 2022 Oct 3;13:921864. doi: 10.3389/fimmu.2022.921864. eCollection 2022.
6
KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases.KDIGO 2021肾小球疾病管理临床实践指南。
Kidney Int. 2021 Oct;100(4S):S1-S276. doi: 10.1016/j.kint.2021.05.021.
7
IgA vasculitis with nephritis: update of pathogenesis with clinical implications.IgA 血管炎伴肾炎：发病机制的最新进展及其临床意义。
Pediatr Nephrol. 2022 Apr;37(4):719-733. doi: 10.1007/s00467-021-04950-y. Epub 2021 Apr 5.
8
Henoch-Schönlein Purpura (IgA Vasculitis): Rapid Evidence Review.过敏性紫癜（IgA 血管炎）：快速证据回顾。
Am Fam Physician. 2020 Aug 15;102(4):229-233.
9
Management of cutaneous vasculitis.皮肤血管炎的管理
Presse Med. 2020 Oct;49(3):104033. doi: 10.1016/j.lpm.2020.104033. Epub 2020 Jul 6.
10
Henoch-Schönlein Purpura in Children: An Updated Review.儿童过敏性紫癜：最新综述。
Curr Pediatr Rev. 2020;16(4):265-276. doi: 10.2174/1573396316666200508104708.