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结核病护理级联在南非农村新型家庭接触者干预措施中的应用。

Application of a TB care cascade to a novel household contact intervention in rural South Africa.

作者信息

Linde L, van Niekerk L B, le Roux K W, Wilson M, Brooks M B, van de Water B J

机构信息

Boston University School of Public Health, Boston, USA.

Zithulele District Hospital, Eastern Cape Department of Health, South Africa.

出版信息

Public Health Action. 2024 Dec 1;14(4):186-189. doi: 10.5588/pha.24.0031. eCollection 2024 Dec.

DOI:10.5588/pha.24.0031
PMID:39618836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11604153/
Abstract

Four clinics implemented an intervention to increase TB household contact identification and evaluation in rural Eastern Cape, South Africa. We applied a care cascade framework to assess gaps in evaluation and treatment initiation from April 2021 to June 2023. We identified 1,698 contacts of 287 individuals with TB. The majority of contacts (71%) were screened; 9% of those with symptoms were fully evaluated, and of these, 14% were diagnosed with active TB. This intervention substantially increased TB contact identification and evaluation compared to prior efforts in the same area; however, additional barriers limited the ability to identify and treat secondary cases.

摘要

四家诊所实施了一项干预措施,以增加南非东开普省农村地区结核病家庭接触者的识别和评估。我们应用了一个护理级联框架,以评估2021年4月至2023年6月期间在评估和治疗启动方面存在的差距。我们识别出了287名结核病患者的1698名接触者。大多数接触者(71%)接受了筛查;有症状的接触者中9%得到了全面评估,其中14%被诊断为活动性结核病。与该地区之前的努力相比,这项干预措施大幅增加了结核病接触者的识别和评估;然而,其他障碍限制了识别和治疗二代病例的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3c/11604153/585e57c5b3a0/pha24-0031f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3c/11604153/f043e3224b6e/pha24-0031f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3c/11604153/585e57c5b3a0/pha24-0031f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3c/11604153/f043e3224b6e/pha24-0031f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c3c/11604153/585e57c5b3a0/pha24-0031f2.jpg

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本文引用的文献

1
In-home TB Testing Using GeneXpert Edge is Acceptable, Feasible, and Improves the Proportion of Symptomatic Household Contacts Tested for TB: A Proof-of-Concept Study.使用GeneXpert Edge进行家庭结核检测是可接受的、可行的,并且提高了有症状家庭接触者接受结核检测的比例:一项概念验证研究。
Open Forum Infect Dis. 2024 May 13;11(6):ofae279. doi: 10.1093/ofid/ofae279. eCollection 2024 Jun.
2
Facilitators and barriers to tuberculosis active case findings in low- and middle-income countries: a systematic review of qualitative research.中低收入国家结核病主动发现的促进因素和障碍:定性研究的系统评价。
BMC Infect Dis. 2023 Aug 7;23(1):515. doi: 10.1186/s12879-023-08502-7.
3
Strategies to increase childhood tuberculosis case detection at the primary health care level: Lessons from an active case finding study in Zambia.
提高初级卫生保健水平发现儿童结核病病例的策略:赞比亚主动病例发现研究的经验教训。
PLoS One. 2023 Jul 19;18(7):e0288643. doi: 10.1371/journal.pone.0288643. eCollection 2023.
4
Transforming tuberculosis diagnosis.变革结核病诊断
Nat Microbiol. 2023 May;8(5):756-759. doi: 10.1038/s41564-023-01365-3.
5
A scoping review of patient-centred tuberculosis care interventions: Gaps and opportunities.以患者为中心的结核病护理干预措施的范围综述:差距与机遇
PLOS Glob Public Health. 2023 Feb 2;3(2):e0001357. doi: 10.1371/journal.pgph.0001357. eCollection 2023.
6
Provision of Decentralized TB Care Services: A Detect-Treat-Prevent Strategy for Children and Adolescents Affected by TB.提供分散式结核病护理服务:针对受结核病影响的儿童和青少年的检测-治疗-预防策略
Pathogens. 2021 Dec 1;10(12):1568. doi: 10.3390/pathogens10121568.
7
Screening tests for active pulmonary tuberculosis in children.儿童活动性肺结核筛查试验。
Cochrane Database Syst Rev. 2021 Jun 28;6(6):CD013693. doi: 10.1002/14651858.CD013693.pub2.
8
TB prevention cascade at a district hospital in rural Eastern Cape, South Africa.南非东开普省农村地区一家区级医院的结核病预防流程
Public Health Action. 2021 Jun 21;11(2):97-100. doi: 10.5588/pha.20.0055.
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Clin Infect Dis. 2020 Oct 23;71(7):1627-1634. doi: 10.1093/cid/ciz1044.
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Constructing care cascades for active tuberculosis: A strategy for program monitoring and identifying gaps in quality of care.构建活动性肺结核护理链:一种用于监测项目和识别护理质量差距的策略。
PLoS Med. 2019 Feb 27;16(2):e1002754. doi: 10.1371/journal.pmed.1002754. eCollection 2019 Feb.