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对抗逆转录病毒疗法有反应的难治性HIV相关格林-巴利综合征:一例报告

Refractory HIV-Associated Guillain-Barré Syndrome Responsive to Antiretroviral Therapy: A Case Report.

作者信息

Coyle Sean, Cormack Ian Sutherland

机构信息

Heath Clinic, Croydon University Hospital, Croydon, London, UK.

出版信息

Case Rep Infect Dis. 2024 Nov 20;2024:7292001. doi: 10.1155/crdi/7292001. eCollection 2024.

DOI:10.1155/crdi/7292001
PMID:39619280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11606698/
Abstract

Guillain-Barré Syndrome (GBS) is an acute polyneuropathy commonly preceded by infection, with growing recognition of the human immunodeficiency virus (HIV) as a trigger. We present a case of a 44-year-old male with HIV-associated GBS refractory to intravenous immunoglobulin (IVIG) therapy, who achieved remission upon starting highly active antireroviral therapy (HAART). There remains a lack of consensus on the management of this condition across the spectrum of disease, and the interplay between the therapeutic options is poorly understood. This report aims to add to the current body of knowledge on this rare condition and highlight the need for retrospective analysis of the currently available literature.

摘要

吉兰-巴雷综合征(GBS)是一种急性多发性神经病,通常在感染后发病,人们越来越认识到人类免疫缺陷病毒(HIV)是其诱发因素。我们报告一例44岁男性HIV相关性GBS患者,该患者对静脉注射免疫球蛋白(IVIG)治疗无效,但在开始高效抗逆转录病毒治疗(HAART)后病情缓解。对于这种疾病在整个病程中的管理,目前仍缺乏共识,而且对各种治疗选择之间的相互作用了解甚少。本报告旨在补充关于这种罕见疾病的现有知识,并强调对现有文献进行回顾性分析的必要性。

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本文引用的文献

1
The Peculiarity of Infection and Immunity Correlated with Guillain-Barré Syndrome in the HIV-Infected Population.人类免疫缺陷病毒(HIV)感染人群中与吉兰-巴雷综合征相关的感染及免疫特性
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2
Triggers of Guillain-Barré Syndrome: Predominates.吉兰-巴雷综合征的诱因:主要为。
Int J Mol Sci. 2022 Nov 17;23(22):14222. doi: 10.3390/ijms232214222.
3
Intravenous immunoglobulin therapy for HIV-associated Guillain-Barré syndrome.静脉注射免疫球蛋白治疗 HIV 相关性吉兰-巴雷综合征。
Int Immunopharmacol. 2022 Nov;112:109192. doi: 10.1016/j.intimp.2022.109192. Epub 2022 Sep 22.
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Guillain-Barré syndrome.格林-巴利综合征。
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Guillain-Barré Syndrome with Fatal Outcome during HIV-1-Seroconversion: A Case Report.HIV-1血清转化期出现致命结局的吉兰-巴雷综合征:一例报告
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Functional recovery of untreated human immunodeficiency virus-associated Guillain-Barré syndrome: a case report.未经治疗的人类免疫缺陷病毒相关性格林-巴利综合征的功能恢复:一例报告。
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Episodes of Guillain-Barré syndrome associated with the acute phase of HIV-1 infection and with recurrence of viremia.吉兰-巴雷综合征发作与HIV-1感染急性期及病毒血症复发相关。
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