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粟粒性肺结核合并急性呼吸窘迫综合征病程中的弥散性血管内凝血

Disseminated Intravascular Coagulation during a Course of Miliary Tuberculosis with Acute Respiratory Distress Syndrome.

作者信息

Sharma Kapil, Jaryal Ajay, Sharma Sumita, Rana Lokesh

机构信息

Department of General Medicine, AIIMS, Bilaspur, Himachal Pradesh, India.

Department of Biochemistry, AIIMS, Bilaspur, Himachal Pradesh, India.

出版信息

J Glob Infect Dis. 2024 May 24;16(3):120-122. doi: 10.4103/jgid.jgid_202_23. eCollection 2024 Jul-Sep.

DOI:10.4103/jgid.jgid_202_23
PMID:39619371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11606543/
Abstract

Miliary tuberculosis (TB) can occasionally lead to acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC). In this case report, we present the case of an 18-year-old male who was diagnosed with miliary TB based on miliary shadows on X-ray and computed tomography of the chest, as well as positivity for mycobacterium TB in endotracheal aspirate by cartridge-based nucleic acid amplification. The patient's hospital stay was complicated by ARDS and DIC, which was successfully managed with ventilatory support, administration of antitubercular treatment, systemic corticosteroids, and blood products.

摘要

粟粒性肺结核偶尔可导致急性呼吸窘迫综合征（ARDS）和弥散性血管内凝血（DIC）。在本病例报告中，我们介绍了一名18岁男性患者，该患者根据胸部X线和计算机断层扫描显示的粟粒状阴影以及基于盒式核酸扩增的气管内吸出物中结核分枝杆菌呈阳性而被诊断为粟粒性肺结核。患者住院期间并发ARDS和DIC，通过通气支持、抗结核治疗、全身使用糖皮质激素和血液制品成功治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6310/11606543/6db0b0d1d589/JGID-16-120-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6310/11606543/4f74dd926404/JGID-16-120-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6310/11606543/6db0b0d1d589/JGID-16-120-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6310/11606543/4f74dd926404/JGID-16-120-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6310/11606543/6db0b0d1d589/JGID-16-120-g002.jpg

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本文引用的文献

1
Miliary Tuberculosis with Acute Respiratory Distress Syndrome: A Deadly Combination.粟粒性肺结核合并急性呼吸窘迫综合征：一种致命组合。
Cureus. 2023 Jan 18;15(1):e33944. doi: 10.7759/cureus.33944. eCollection 2023 Jan.
2
Miliary tuberculosis: A new look at an old foe.粟粒性肺结核：对老对手的新审视。
J Clin Tuberc Other Mycobact Dis. 2016 Mar 18;3:13-27. doi: 10.1016/j.jctube.2016.03.003. eCollection 2016 May.
3
Tuberculous pneumonia-induced severe ARDS complicated with DIC in a female child: a case of successful treatment.
女性儿童结核性肺炎所致严重 ARDS 合并 DIC：成功治疗一例。
BMC Infect Dis. 2018 Jul 3;18(1):294. doi: 10.1186/s12879-018-3215-5.
4
Corrigendum to "Miliary Tuberculosis Presenting with ARDS and Shock: A Case Report and Challenges in Current Management and Diagnosis".《粟粒性肺结核伴急性呼吸窘迫综合征和休克：一例报告及当前管理与诊断中的挑战》勘误
Case Rep Crit Care. 2018 May 14;2018:2073618. doi: 10.1155/2018/2073618. eCollection 2018.
5
Miliary tuberculosis: Epidemiologicaland clinical analysis of large-case series from moderate to low tuberculosis endemic Country.粟粒性肺结核：来自结核病中度至低度流行国家的大病例系列的流行病学和临床分析。
Medicine (Baltimore). 2017 Feb;96(5):e5875. doi: 10.1097/MD.0000000000005875.
6
Acute respiratory distress syndrome in disseminated tuberculosis: an uncommon association.播散性肺结核中的急性呼吸窘迫综合征：一种罕见的关联。
Int J Tuberc Lung Dis. 2016 Feb;20(2):271-5. doi: 10.5588/ijtld.15.0357.
7
[A case of miliary tuberculosis complicated by disseminated intravascular coagulation and acute respiratory distress syndrome successfully treated with recombinant human soluble thrombomodulin].[1例粟粒性肺结核合并弥散性血管内凝血及急性呼吸窘迫综合征经重组人可溶性血栓调节蛋白成功治疗的病例]
Kekkaku. 2012 Dec;87(12):771-6.
8
[The adult respiratory stress syndrome and septic shock associated with tuberculosis].[成人呼吸窘迫综合征与结核病相关的感染性休克]
Rev Clin Esp. 1995 Mar;195(3):160-3.