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快速现场评估:一项关于支气管内超声引导下经支气管针吸活检以加速诊断的前瞻性观察研究。

Rapid Onsite Evaluation: A Prospective Observational Study of Endobronchial Ultrasound-Guided Transbronchial Needle Aspirates to Expedite Diagnosis.

作者信息

Mercer Carolyn, Brackenborough Kate, Davidson Colette, Nisar Tosia, Shambayati Behdad, Cunningham Rupinder, Howarth Ben, Jayadev Anita

机构信息

Respiratory Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, United Kingdom.

Respiratory Medicine, Frimley Park Hospital, Frimley Health NHS Foundation Trust, Frimley, United Kingdom.

出版信息

Br J Biomed Sci. 2024 Nov 14;81:12938. doi: 10.3389/bjbs.2024.12938. eCollection 2024.

Abstract

Biomedical scientists (BMS) can report sample adequacy during EBUS TBNA using rapid on-site evaluation (ROSE). Despite being able to report exfoliative samples such as pleural fluid cytology and bronchial washings, they are usually not permitted to offer a preliminary diagnostic impression of EBUS TBNA samples. Experienced biomedical scientists can provide a reliable diagnostic impression during ROSE for EBUS samples, with sensitivity and specificity comparable to cytopathologist reporting. This work represents an advance in biomedical science because it provides evidence a BMS can safely and accurately provide a real time cytopathological impression from EBUS TBNA sampling, which could positively impact patient pathways.

摘要

生物医学科学家(BMS)可以在超声支气管镜引导下经支气管针吸活检(EBUS TBNA)过程中,通过快速现场评估(ROSE)报告样本的充足性。尽管能够报告诸如胸腔积液细胞学检查和支气管冲洗等脱落细胞样本,但他们通常不被允许对EBUS TBNA样本给出初步诊断印象。经验丰富的生物医学科学家可以在ROSE过程中为EBUS样本提供可靠的诊断印象,其敏感性和特异性与细胞病理学家的报告相当。这项工作代表了生物医学科学的一项进展,因为它提供了证据表明,生物医学科学家可以安全、准确地从EBUS TBNA采样中提供实时细胞病理学印象,这可能对患者的诊疗流程产生积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fca1/11605290/ac6ca69dc243/bjbs-81-12938-g001.jpg

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