Hartzen S H, Skaarup P, Bremmelgaard A
Urol Int. 1986;41(1):64-6. doi: 10.1159/000281162.
The value of clinical decision on antibiotic treatment of fever episodes following transurethral resection of the prostate was assessed in 134 patients. Besides bacteriuria, need of blood transfusions and various catheter problems were associated with a significant number of fever episodes. The majority of patients with fever not given antibiotic therapy had negative urine cultures (90%), whereas 41% of the patients with fever treated with antibiotics showed negative urine cultures indicating an overtreatment of these patients. Out of the total number of patients, only 10% with subsequent negative urine cultures received antibiotics, a figure which should be compared to the inevitable rate of overtreatment when general antibiotic prophylaxis is preferred.
对134例经尿道前列腺切除术后发热患者抗生素治疗的临床决策价值进行了评估。除菌尿外，输血需求和各种导管问题与大量发热事件相关。大多数未接受抗生素治疗的发热患者尿培养结果为阴性（90%），而接受抗生素治疗的发热患者中有41%尿培养结果为阴性，这表明这些患者存在过度治疗。在所有患者中，仅有10%随后尿培养结果为阴性的患者接受了抗生素治疗，这一数字应与普遍采用抗生素预防时不可避免的过度治疗率进行比较。
