Benedictus G, Haagsma J
Vet Q. 1986 Jan;8(1):5-11. doi: 10.1080/01652176.1986.9694012.
Lymph node biopsy was performed on animals older than nine months on a dairy farm which carried 223 animals and was severely affected by paratuberculosis. Biopsies were examined histologically and bacteriologically for the presence of M. paratuberculosis infection. In this way paratuberculosis infection was diagnosed in 29 animals, in which other diagnostic methods (serum complement fixation test, intradermal johnin test and microscopic examination of the faeces) produced negative results. The value of lymph node biopsy is the early detection of infected animals. In the two years after the biopsies, no further cases of clinical paratuberculosis were detected on the affected farm, although infection with M. paratuberculosis persisted.
对一家存栏223头奶牛且受副结核病严重影响的奶牛场中9个月以上的动物进行了淋巴结活检。对活检样本进行了组织学和细菌学检查，以确定是否存在副结核分枝杆菌感染。通过这种方式，在29只动物中诊断出副结核感染，而其他诊断方法（血清补体结合试验、皮内注射结核菌素试验和粪便显微镜检查）结果均为阴性。淋巴结活检的价值在于早期发现感染动物。活检后的两年里，尽管副结核分枝杆菌感染依然存在，但在受影响的农场未再检测到临床副结核病病例。
