Haehn Daniela A, Chadha Ryan M, Porter Steven B, Pathak Ram A, Lyon Timothy D, Hochwald Alex P, Dora Chandler D
Mayo Clinic Florida Department of Urology, Jacksonville, FL.
Mayo Clinic Florida Department of Anesthesia and Perioperative Medicine, Jacksonville, FL.
Urology. 2025 Feb;196:260-264. doi: 10.1016/j.urology.2024.11.058. Epub 2024 Nov 30.
To determine if using spinal anesthesia (SA) for holmium laser enucleation of the prostate (HoLEP) impacted the ability to perform same-day discharge (SDD) compared to a prostate volume-matched cohort undergoing HoLEP under general anesthesia (GA).
From January 1, 2021 to March 28, 2024, 995 men underwent HoLEP by a single surgeon. Three hundred eleven were identified who had SA and a recorded preoperative prostate volume. Propensity score matching based on prostate volume was performed with the remaining cohort who received GA in a 1:1 ratio. The primary outcome was rate of SDD.
When comparing SDD between the two groups, 84% of SA patients had SDD compared to 74% of GA patients (P-value .002). The operative time for SA was significantly shorter than GA (89 vs 101 minutes P-value <.001). The total operating room time (wheels-in to wheels-out) including anesthesia induction for SA was significantly shorter than GA (119 vs 128 minutes P-value .0003). There were no significant differences in early catheter reinsertion, emergency department visits, complications, or postoperative serum prostate-specific antigen measured at 3months.
Utilizing SA for HoLEP did not preclude SDD compared to a prostate volume-matched cohort who underwent HoLEP under GA. In fact, SDD were higher in the SA cohort without a corresponding increase in emergency department visits or catheter reinsertion.
与接受全身麻醉(GA)进行钬激光前列腺剜除术(HoLEP)的前列腺体积匹配队列相比,确定使用脊髓麻醉(SA)进行HoLEP是否会影响当日出院(SDD)的能力。
从2021年1月1日至2024年3月28日,995名男性由一名外科医生进行了HoLEP手术。确定了311名接受SA且术前前列腺体积有记录的患者。对其余接受GA的队列按1:1的比例进行基于前列腺体积的倾向评分匹配。主要结局是SDD率。
比较两组的SDD情况时,84%的SA患者实现了SDD,而GA患者为74%(P值为0.002)。SA的手术时间明显短于GA(89分钟对101分钟,P值<0.001)。包括SA麻醉诱导在内的总手术室时间(推入到推出)明显短于GA(119分钟对128分钟,P值为0.0003)。在早期导尿管重新插入、急诊就诊、并发症或3个月时测量的术后血清前列腺特异性抗原方面没有显著差异。
与在GA下进行HoLEP的前列腺体积匹配队列相比,使用SA进行HoLEP并不排除SDD。事实上,SA队列中的SDD率更高,且急诊就诊或导尿管重新插入没有相应增加。