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[检测胃肠道癌患者癌胚抗原的临床及预后意义]

[Clinical and prognostic significance of determining the carcinoembryonic antigen in patients with gastrointestinal cancer].

作者信息

Vlakhov N, Dimitrova S, Koev Ch, Vladimirov V, Bozhinov T

出版信息

Vopr Onkol. 1986;32(2):73-6.

PMID:3962245
Abstract

The paper discusses the results of a radioimmunologic assay of carcinoembryonic antigen (CEA) levels in 100 cases of gastrointestinal cancer. CEA--PRIST kits (Phadebas, Sweden) and NGR-603 automatic gamma-unit (Tesla, Czechoslovakia) were employed. The test proved to be highly instrumental in the preoperative evaluation of prognosis and early detection of recurrence and metastasis. CEA concentrations within 30-50 ng/ml are highly suggestive of recurrence or metastases, whereas 50-100 ng/ml should serve an indicator of organ dissemination. The test is useful in assessing the effectiveness of treatment in the course of follow-up.

摘要

本文讨论了对100例胃肠道癌患者癌胚抗原(CEA)水平进行放射免疫测定的结果。使用了CEA - PRIST试剂盒(瑞典法玛西亚公司)和NGR - 603自动γ仪(捷克斯洛伐克特斯拉公司)。该检测在术前预后评估以及复发和转移的早期检测中被证明具有很高的作用。CEA浓度在30 - 50 ng/ml高度提示复发或转移,而50 - 100 ng/ml应作为器官播散的指标。该检测在随访过程中评估治疗效果方面很有用。

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