Valenzuela-Fuenzalida Juan José, Rodríguez-Osorio Benjamín, Salgado-Torres Cristian, Nova-Baeza Pablo, Orellana-Donoso Mathias, Bruna-Mejías Alejandro, Avila-Sepulveda Roberto, Becerra-Farfán Álvaro, Rodríguez-Luengo Macarena, Sanchis-Gimeno Juan, Granite Guinevere, Gutiérrez-Espinoza Héctor
Departamento de Morfología, Facultad de Medicina, Universidad Andrés Bello, Santiago, 8370146, Chile.
Departamento de Ciencias Química y Biológicas, Facultad de Ciencias de la Salud, Universidad Bernardo O'Higgins, Santiago, 8370993, Chile.
Sci Rep. 2024 Dec 3;14(1):30002. doi: 10.1038/s41598-024-81543-3.
The hepatic portal vein is the main vascular route responsible for collecting blood from the liver, spleen, pancreas, stomach, gallbladder, and intestines. Its key function is to metabolize the components acquired from the blood. The objective of this study was to analyze the characteristics of HPV variants and understand the possible clinical considerations that arise with them. The databases Medline, Scopus, Web of Science, Google Scholar, Cumulative Index to Nursing and Allied Health Literature and Latin American and Caribbean Literature in Health Sciences were researched until January 2024. Tree authors independently performed the search, study selection and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies. Pooled prevalence was estimated using a random effects model. A total of 31 studies met the established selection criteria. In this study, 21 articles were included for the meta-analysis with a total of 51,244 subjects. Of these 21 articles, the topics studied came mainly from Europe and Asia, with three (n = 554; 1.08%) and 11 articles (n = 50,090; 97.75%) respectively, also having six articles from North America (n = 442; 0.86%) and one from Africa (n = 158; 0.31%), discarding the articles from Oceania and South America. For the HPV trifurcation variant, it was 8% (CI = 7-10%). Apropos the right posterior portal vein variant, as the primary tributary from the main HPV, it was 7% (CI = 4-11%). About the right anterior portal vein variant originating from the left portal vein, it was 4% (CI = 1-6%). Finally, the prevalence of the isolated variants was 2% (CI = 1-3%). The knowledge of HPV and its anatomical variants is of utmost importance for both medical professionals and anatomists, as it is one of the vessels that collects blood from many important viscera found in the abdominal cavity, any structural alteration could be crucial in diagnosis and surgical procedures.
肝门静脉是负责收集来自肝脏、脾脏、胰腺、胃、胆囊和肠道血液的主要血管路径。其关键功能是代谢从血液中获取的成分。本研究的目的是分析肝门静脉变异的特征，并了解与之相关的可能临床考量。检索了Medline、Scopus、科学网、谷歌学术、护理及相关健康文献累积索引以及拉丁美洲和加勒比地区健康科学文献数据库，直至2024年1月。三位作者独立进行检索、研究筛选和数据提取。使用解剖学研究的保证工具评估方法学质量。采用随机效应模型估计合并患病率。共有31项研究符合既定的纳入标准。在本研究中，纳入21篇文章进行荟萃分析，共有51244名受试者。在这21篇文章中，所研究的主题主要来自欧洲和亚洲，分别有3篇（n = 554；1.08%）和11篇文章（n = 50090；97.75%），也有6篇来自北美洲（n = 442；0.86%）和1篇来自非洲（n = 158；0.31%），未纳入大洋洲和南美洲的文章。对于肝门静脉三分叉变异，其发生率为8%（可信区间=7 - 10%）。关于作为主要肝门静脉主要分支的右后门静脉变异，其发生率为7%（可信区间=4 - 11%）。源于左门静脉的右前门静脉变异发生率为4%（可信区间=1 - 6%）。最后，孤立变异的发生率为2%（可信区间=1 - 3%）。肝门静脉及其解剖变异的知识对医学专业人员和解剖学家都至关重要，因为它是收集腹腔内许多重要脏器血液的血管之一，任何结构改变在诊断和手术过程中都可能至关重要。
