[Detection and treatment of chronic renal failure in general practice, central problem of the responsibilities of the nephrology specialist].

Renal failures develops independently from different primary kidney diseases into the uniform syndrome of uremia. Many partial functions or regulatory systems of the organism are involved (anemia, hypertension, polyneuropathy, mineral and electrolyte metabolism, glucose tolerance etc.). Responsibilities of nephrological guidance are early diagnosis and compensatory treatment of such deviations in order to lower risks during the still conservatively treatable phase of the disease. Prognosis and quality of life in renal replacement therapy can be improved.