小儿肺泡软部肉瘤的超声特征：一项回顾性分析
Ultrasound characteristics of alveolar soft part sarcoma in pediatric patients: a retrospective analysis.
作者信息
Wang Siwei, Wang Yu, Xu Jiatong, Ren Qinghua, Hu Yanxiu, Jia Liqun, Wang Xiaoman
机构信息
Department of Ultrasound, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No.56 Nan Li Shi Road, Xi Cheng District, Beijing, 100045, China.
Department of Pathology, Beijing Children's Hospital Capital Medical University, National Center for Children's Health, No.56 Nan Li Shi Road, Xi Cheng District, Beijing, 100045, China.
出版信息
BMC Cancer. 2024 Dec 2;24(1):1484. doi: 10.1186/s12885-024-13262-x.
OBJECTIVE
This study aims to review and summarize the ultrasound characteristics of alveolar soft part sarcoma (ASPS) in children.
METHODS
We retrospectively analyzed 20 pediatric ASPS cases confirmed by surgery or biopsy at our hospital between January 2014 and January 2024. Clinical data, including age, sex, symptoms, and tumor location, were collected. Ultrasound reports and images were reviewed to extract data on tumor size, boundaries, echogenicity, and vascularity.
RESULTS
The study included 20 children with ASPS. The tumors were located in the trunk and limbs (50%), as well as in the head and neck (50%). Compared with tumors in the trunk and limbs, head and neck tumors were smaller in size, had more pronounced symptoms, and had a lower incidence of metastasis. Ultrasound features predominantly included hypoechoic masses with clear boundaries, heterogeneous echogenicity, and rich internal and surrounding vascularity, often with tortuous and dilated blood vessels. Eight patients had distant metastases at diagnosis, seven of which involved the lungs. There was a moderate correlation between tumor size and the risk of distant metastasis (r = 0.64).
CONCLUSION
Understanding the clinical and ultrasound characteristics of pediatric ASPS can facilitate earlier and more accurate diagnosis.
目的
本研究旨在回顾和总结儿童肺泡软组织肉瘤（ASPS）的超声特征。
方法
我们回顾性分析了2014年1月至2024年1月期间在我院经手术或活检确诊的20例儿童ASPS病例。收集了临床数据，包括年龄、性别、症状和肿瘤位置。回顾超声报告和图像以提取有关肿瘤大小、边界、回声性和血管分布的数据。
结果
该研究纳入了20例患有ASPS的儿童。肿瘤位于躯干和四肢（50%）以及头颈部（50%）。与躯干和四肢的肿瘤相比，头颈部肿瘤体积较小，症状更明显，转移发生率较低。超声特征主要包括边界清晰的低回声肿块、回声不均匀以及内部和周围血管丰富，血管常迂曲扩张。8例患者在诊断时出现远处转移，其中7例累及肺部。肿瘤大小与远处转移风险之间存在中度相关性（r = 0.64）。
结论
了解儿童ASPS的临床和超声特征有助于更早、更准确地诊断。
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