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便携式低场磁共振成像在脑血管疾病中的最新进展

Recent advances in portable, low-field magnetic resonance imaging in cerebrovascular disease.

作者信息

Zabinska Julia, de Havenon Adam, Sheth Kevin N

机构信息

Department of Neurology, Yale Center for Brain & Mind Health, Yale School of Medicine, New Haven, Connecticut, USA.

出版信息

Curr Opin Neurol. 2025 Feb 1;38(1):35-39. doi: 10.1097/WCO.0000000000001338. Epub 2024 Dec 2.

Abstract

PURPOSE OF REVIEW

This review aims to describe recent advances in low-field (0.064 T) magnetic resonance imaging (LF-MRI) of cerebrovascular disease, including ischemic and hemorrhagic stroke and white matter hyperintensities.

RECENT FINDINGS

Since 2023, several studies have highlighted the rapidly changing landscape of portable, low-field MRI (LF-MRI) and its applications in stroke and cerebrovascular disease. The advantages of using LF-MRI in these settings are multifold: cheaper and dynamic imaging of this patient population confers closer observation during the acute and chronic stages of cerebrovascular disease. Initial deployments of the device span a variety of acute and emergency settings, including imaging around thrombolytic administration, endovascular reperfusion, intracerebral hemorrhage management, and cardiovascular intensive care. LF-MRI also has an important role in cerebrovascular disease monitoring and prevention, namely white matter hyperintensity (WMH) progression and vascular and Alzheimer's dementia. Early studies suggest reliable sensitivity and specificity for these pathologies. With further improvements to LF-MRI hardware, software and postprocessing on the horizon, we anticipate the device's ability to provide inexpensive and flexible neuroimaging to a wide array of healthcare settings that treat, prevent, and manage cerebrovascular disease.

SUMMARY

Recent studies indicate that LF-MRI promotes rapid, cost-effective, and clinically useful neuroimaging at various clinical timepoints throughout stroke and cerebrovascular disease progression and management.

摘要

综述目的

本综述旨在描述脑血管疾病低场(0.064 T)磁共振成像(LF-MRI)的最新进展,包括缺血性和出血性中风以及白质高信号。

最新发现

自2023年以来,多项研究强调了便携式低场MRI(LF-MRI)及其在中风和脑血管疾病中的应用迅速变化的格局。在这些情况下使用LF-MRI的优势是多方面的:对该患者群体而言成本更低且能进行动态成像,有助于在脑血管疾病的急性和慢性阶段进行更密切的观察。该设备的初步部署涵盖了各种急性和紧急情况,包括溶栓给药、血管内再灌注、脑出血管理及心血管重症监护期间的成像。LF-MRI在脑血管疾病监测和预防方面也发挥着重要作用,即白质高信号(WMH)进展以及血管性和阿尔茨海默病性痴呆。早期研究表明对这些病变具有可靠的敏感性和特异性。随着LF-MRI硬件、软件和后处理技术的进一步改进,我们预计该设备能够为广泛治疗、预防和管理脑血管疾病的医疗机构提供廉价且灵活的神经成像。

总结

最近的研究表明,LF-MRI在中风和脑血管疾病进展及管理的各个临床时间点促进了快速、经济高效且具有临床实用性的神经成像。

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