Ahmadian David, Wehbi Nader, Gleadhill Claire M, Monahan Natalie, Gallego Charles J, Skirko Jonathan R, Yip Helena T
College of Medicine University of Arizona Tucson Arizona USA.
College of Medicine University of Arizona Phoenix Arizona USA.
Laryngoscope Investig Otolaryngol. 2024 Dec 2;9(6):e70039. doi: 10.1002/lio2.70039. eCollection 2024 Dec.
Vocal cord dysfunction (VCD) is a complex disorder characterized by episodic adduction of the vocal folds during inspiration and expiration, which can lead to dyspnea, wheezing, cough, and acute-onset respiratory distress. Currently, there is a lack of standardized criteria among treating physicians across multiple disciplines, including otolaryngologists, pulmonologists, allergists, and speech and language pathologists, for diagnosis and treatment of VCD, although laryngeal-respiratory retraining therapy (LRT) has emerged as the preferred treatment modality.
In the present study, we examined the efficacy of LRT in patients presenting with a clinical diagnosis of VCD in the presence and absence of laryngeal adduction on laryngoscopy.
Overall, 74.1% of the cohort showed a response to LRT, of which 62.1% were partial and 12.1% were significant responses. When comparing between patients with and without laryngeal adduction on laryngoscopy, there were no significant differences in the number of sessions of LRT undertaken, mean time to response, and overall response rate between the groups.
Our findings suggest that LRT should be utilized for all patients presenting with symptoms of VCD, even in the absence of laryngeal adduction on laryngoscopy.
声带功能障碍（VCD）是一种复杂的病症，其特征为在吸气和呼气期间声带间歇性内收，这可导致呼吸困难、喘息、咳嗽及急性发作的呼吸窘迫。目前，包括耳鼻喉科医生、肺科医生、过敏症专科医生以及言语和语言病理学家在内的多个学科的治疗医生在VCD的诊断和治疗方面缺乏标准化标准，尽管喉呼吸再训练疗法（LRT）已成为首选的治疗方式。
在本研究中，我们检查了LRT对临床诊断为VCD且喉镜检查时存在或不存在喉部内收的患者的疗效。
总体而言，74.1%的队列对LRT有反应，其中62.1%为部分反应，12.1%为显著反应。在喉镜检查时有或无喉部内收的患者之间进行比较时，两组在接受LRT的疗程数、平均反应时间和总体反应率方面均无显著差异。
我们的研究结果表明，即使喉镜检查时不存在喉部内收，LRT也应用于所有出现VCD症状的患者。
