Patel Dhruvil Vinaybhai, Narayana Chandan Alenahalli, Harish Rachana, Bhatia Harsh, Mehta Shubh, Bhatta Om Prakash, Singh Manjeet
Depatrment of Neurology, GMERS Medical College Gandhinagar, Gandhinagar, Gujarat 382012, India.
Bangalore Medical College and Research Institute, Bengaluru, Karnataka 560002, India.
Med Int (Lond). 2024 Nov 13;5(1):5. doi: 10.3892/mi.2024.204. eCollection 2025 Jan-Feb.
Patent foramen ovale (PFO) is a common congenital heart defect that can contribute to cryptogenic stroke, particularly in younger patients lacking traditional risk factors. The present study describes the case of a 14-year-old male patient who experienced an acute ischemic stroke without identifiable atheroembolic risk factors. Comprehensive diagnostic imaging revealed a marked right-to-left shunt through a PFO, identified as the probable cause of the stroke. The patient was treated with dual antiplatelet therapy and subsequently underwent successful percutaneous PFO closure. At 6 months following the procedure, the patient exhibited notable neurological recovery. The present case report highlights the critical need for evaluating PFO as a potential etiology of cryptogenic stroke in younger populations, emphasizing the advantages of a multidisciplinary approach and timely intervention in preventing recurrent events.
卵圆孔未闭(PFO)是一种常见的先天性心脏缺陷,可导致不明原因的卒中,尤其是在缺乏传统危险因素的年轻患者中。本研究描述了一名14岁男性患者的病例,该患者发生急性缺血性卒中,无明确的动脉粥样硬化栓塞危险因素。综合诊断成像显示通过卵圆孔未闭存在明显的右向左分流,确定为卒中的可能原因。该患者接受了双联抗血小板治疗,随后成功进行了经皮卵圆孔未闭封堵术。术后6个月,患者神经功能显著恢复。本病例报告强调了评估卵圆孔未闭作为年轻人群不明原因卒中潜在病因的迫切需要,强调了多学科方法和及时干预在预防复发事件中的优势。