Alzahrani Raghad S, Ezzi Suzana, Alghamdi Mohammed M, Alsudais Ali S, Yahya Nawal, Aljuaid Fetoon M, Radi Suhaib
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
College of Medicine, King Abdullah International Medical Research Center, Jeddah, SAU.
Cureus. 2024 Nov 1;16(11):e72837. doi: 10.7759/cureus.72837. eCollection 2024 Nov.
Background Radioactive iodine (iodine-131) therapy is widely used for treating thyroid cancer. However, the knowledge and practices of healthcare professionals in preparing patients for radioactive iodine therapy may vary, potentially affecting patient outcomes. Objective This study aimed to evaluate the knowledge and practices of healthcare professionals at King Abdulaziz Medical City (KAMC) in Jeddah, regarding the preparation of patients with thyroid cancer for radioactive iodine therapy. Methodology A cross-sectional study was conducted using an electronic survey distributed to endocrinology consultants, fellows, medical residents, radiologists, nuclear medicine technicians, and nurses at KAMC. The survey assessed participants' knowledge and practices related to radioactive iodine preparation. Using JMP 17 database software (JMP, Cary, NC), descriptive and inferential statistical analyses were performed and qualitative data were analyzed thematically. Results The study included 30 participants, half of whom had five years of experience or less (43.33%, n=13). More than half of the respondents reported involvement in the administration of iodine-131 (56.67%, n=17). Only around half the participants correctly identified certain aspects, such as the need for recombinant human thyroid stimulating hormone (TSH) prior to iodine therapy (56.67%, n=17), adherence to a low-iodine diet (43.33%, n=13), screening female patients for pregnancy (76.67%, n=23), the duration for which women should avoid pregnancy (56.67%, n=17) and patient education on the side effects and distance precautions when sleeping with others (48%, n=12). The study found a significant association between involvement in the administration or supervision of iodine-131 and knowledge of the necessary medication prior to treatment (p=0.0431 for correct choice and p=0.0117 for correct dosage). Conclusion The study revealed knowledge gaps among healthcare professionals at KAMC regarding the preparation of patients with thyroid cancer for radioactive iodine therapy. It emphasizes the need for educational and training initiatives to improve healthcare professionals' knowledge and awareness in this area. Addressing these knowledge gaps can enhance patient safety and optimize the effectiveness of radioactive iodine therapy.
背景 放射性碘（碘 - 131）疗法被广泛用于治疗甲状腺癌。然而，医疗保健专业人员在为患者准备放射性碘治疗方面的知识和做法可能存在差异，这可能会影响患者的治疗结果。目的 本研究旨在评估吉达阿卜杜勒阿齐兹国王医疗城（KAMC）的医疗保健专业人员在为甲状腺癌患者准备放射性碘治疗方面的知识和做法。方法 采用横断面研究，通过电子调查问卷对KAMC的内分泌科顾问、研究员、住院医师、放射科医生、核医学技术人员和护士进行调查。该调查评估了参与者与放射性碘准备相关的知识和做法。使用JMP 17数据库软件（JMP，北卡罗来纳州卡里）进行描述性和推断性统计分析，并对定性数据进行主题分析。结果 该研究包括30名参与者，其中一半有五年或更少的工作经验（43.33%，n = 13）。超过一半的受访者表示参与过碘 - 131的给药（56.67%，n = 17）。只有大约一半的参与者正确识别了某些方面，例如碘治疗前需要重组人促甲状腺激素（TSH）（56.67%，n = 17）、坚持低碘饮食（43.33%，n = 13）、对女性患者进行妊娠筛查（76.67%，n = 23）、女性应避免妊娠的持续时间（56.67%，n = 17）以及对患者进行关于副作用和与他人睡觉时的距离预防措施的教育（48%，n = 12）。研究发现参与碘 - 131给药或监督与治疗前必要药物知识之间存在显著关联（正确选择的p = 0.0431，正确剂量的p = 0.0117）。结论 该研究揭示了KAMC的医疗保健专业人员在为甲状腺癌患者准备放射性碘治疗方面存在知识差距。它强调需要开展教育和培训举措，以提高医疗保健专业人员在这一领域的知识和意识。解决这些知识差距可以提高患者安全性并优化放射性碘治疗的有效性。
