老年青光眼和非青光眼患者的前房角发育异常。一项遮蔽式裂隙灯和前房角镜检查研究。

Goniodysgenesis in elderly glaucoma and non-glaucoma patients. A masked slit-lamp and gonioscopy study.

作者信息

Svedbergh B, Alm A, Amér B, Jerndal T, Thorburn W

出版信息

Acta Ophthalmol (Copenh). 1986 Feb;64(1):45-51. doi: 10.1111/j.1755-3768.1986.tb06870.x.

DOI:10.1111/j.1755-3768.1986.tb06870.x

Abstract

The aim was to elucidate whether goniodysgenesis is more frequently observed in elderly patients with glaucoma, and furthermore, which signs of goniodysgenesis are of importance and most unanimously detected. Thus, 3 examiners evaluated 21 glaucoma patients and 19 non-glaucoma patients in a masked fashion. None of the patients had a first-degree heredity. Gonioscopy, slit-lamp examination and measurements of the corneal and pupillary diameter were performed, in all 26 variables. Significantly (P less than 0.05) more frequent in glaucoma were an increased corneal diameter, scleral overriding, hypoplasia of the pupillary seam, abnormal Schwalbe's line and an opaque pretrabecular membrane (one examiner). Less frequent were a peripupillary yellow pigment ring and pigment stars on the lens. Inter-observer variation was small regarding e.g. corneal diameter but rather large regarding e.g. the pretrabecular membrane.

摘要

目的是阐明在老年青光眼患者中是否更频繁地观察到前房角发育异常，此外，前房角发育异常的哪些体征重要且最一致地被检测到。因此，3名检查者以盲法评估了21例青光眼患者和19例非青光眼患者。所有患者均无一级遗传史。进行了前房角镜检查、裂隙灯检查以及角膜和瞳孔直径的测量，共26项变量。在青光眼中，角膜直径增加、巩膜覆盖、瞳孔缝发育不全、施瓦贝线异常和小梁前膜混浊（一名检查者）明显更常见（P小于0.05）。瞳孔周围黄色色素环和晶状体上的色素星较少见。观察者间在角膜直径等方面的差异较小，但在小梁前膜等方面差异较大。