Olson Elizabeth S, Dong Wei, Applegate Brian E, Charaziak Karolina K, Dewey James B, Frost Brian L, Meenderink Sebastiaan W F, Nam Jong-Hoon, Oghalai John S, Puria Sunil, Ren Tianying, Strimbu C Elliott, van der Heijden Marcel
Department of Otolaryngology - Head and Neck Surgery, Department of Biomedical Engineering, Columbia University, New York City, NY USA.
VA Loma Linda Healthcare System, Loma Linda, CA, USA, Department of Otolaryngology - Head and Neck Surgery, Loma Linda University Health, Loma Linda, CA USA.
Hear Res. 2025 Jan;455:109154. doi: 10.1016/j.heares.2024.109154. Epub 2024 Nov 27.
Beginning in 2006, optical coherence tomography (OCT) has been adapted for use as a vibrometer for hearing research. The application of OCT in this field, particularly for studying cochlear mechanics, represents a revolutionary advance over previous technologies. OCT provides detailed evidence of the motions of components within the organ of Corti, extending beyond the first-encountered surface of observation. By imaging through the bony capsule as well as through the round window membrane, OCT has measured vibration at multiple locations along the cochlear spiral, in vivo, under nearly natural conditions. In this document, we present examples of recent research findings to illustrate the applications of OCT in studying cochlear mechanics in both normal and impaired ears.
从2006年开始，光学相干断层扫描（OCT）已被应用于听力研究中的振动测量。OCT在该领域的应用，特别是在研究耳蜗力学方面，相对于以前的技术是一项革命性的进步。OCT提供了柯蒂氏器内各组成部分运动的详细证据，其观察范围超出了首次遇到的表面。通过对骨囊以及圆窗膜进行成像，OCT在几乎自然的条件下，在体内测量了沿耳蜗螺旋多个位置的振动。在本文中，我们展示了近期研究结果的实例，以说明OCT在研究正常耳朵和受损耳朵的耳蜗力学中的应用。
