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社会剥夺与心房颤动导管消融治疗可及性之间的关系:一项基于人群的研究。

Relationship Between Social Deprivation and Access to Catheter Ablation for Atrial Fibrillation: A Population-Level Study.

作者信息

Katyukha Andriy, Qiu Feng, Qeska Denis, Manoragavan Ragavie, Wijeysundera Harindra C, Cheung Christopher C

机构信息

Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

University of Toronto Department of Medicine, Toronto, Ontario, Canada.

出版信息

JACC Adv. 2024 Nov 18;3(12):101400. doi: 10.1016/j.jacadv.2024.101400. eCollection 2024 Dec.

Abstract

BACKGROUND

Access to catheter ablation for atrial fibrillation (AF) may vary due to social deprivation.

OBJECTIVES

This study sought to characterize the correlation between our outcomes of interest (rates of AF diagnoses, ablation referrals, and procedures) and the association between social deprivation and our outcomes.

METHODS

Rates and correlations of AF diagnoses, ablation referrals, and procedures were reported across 49 census divisions in Ontario, Canada. We used the Ontario Marginalization Index to determine the relationship between dependency, material deprivation, ethnic concentration, and residential instability and our outcomes.

RESULTS

Between April 2016 and March 2020, there were 146,366 patients diagnosed with AF; 6,506 patients were referred for ablation; and 4,673 patients underwent de novo ablation. The median age was 72 years (IQR: 61-81 years; 45% female) for the AF cohort and 62 years (IQR: 55-69 years, 33% to 34% female) for the referral and procedure cohorts. There was geographic variation and a weak concordance between AF diagnoses, ablation referrals, and procedures (correlation coefficients 0.33-0.36). Increased material deprivation was associated with more AF diagnoses (rate ratio [RR]: 1.13), but fewer ablation referrals (RR: 0.49) and procedures (RR: 0.48). Increased residential instability was associated with more AF diagnoses (RR: 1.02), but fewer ablation referrals (RR: 0.63) and procedures (RR: 0.64). Higher ethnic concentration was associated with fewer AF diagnoses, ablation referrals, and procedures.

CONCLUSIONS

In a jurisdiction with universal health care, greater material deprivation and residential instability were associated with more AF diagnoses but less access to ablation, suggesting substantial social gradients in equitable access to AF care.

摘要

背景

由于社会剥夺,房颤(AF)导管消融的可及性可能存在差异。

目的

本研究旨在描述我们感兴趣的结局(房颤诊断率、消融转诊率和手术率)之间的相关性,以及社会剥夺与我们的结局之间的关联。

方法

报告了加拿大安大略省49个人口普查区的房颤诊断率、消融转诊率和手术率及相关性。我们使用安大略省边缘化指数来确定依赖性、物质剥夺、种族集中和居住不稳定性与我们的结局之间的关系。

结果

2016年4月至2020年3月期间,有146366例患者被诊断为房颤;6506例患者被转诊进行消融;4673例患者接受了初次消融。房颤队列的中位年龄为72岁(四分位间距:61 - 81岁;45%为女性),转诊和手术队列的中位年龄为62岁(四分位间距:55 - 69岁,33%至34%为女性)。房颤诊断、消融转诊和手术之间存在地理差异且一致性较弱(相关系数0.33 - 0.36)。物质剥夺增加与更多的房颤诊断相关(率比[RR]:1.13),但消融转诊(RR:0.49)和手术(RR:0.48)较少。居住不稳定性增加与更多的房颤诊断相关(RR:1.02),但消融转诊(RR:0.63)和手术(RR:0.64)较少。种族集中度较高与较少的房颤诊断、消融转诊和手术相关。

结论

在一个拥有全民医疗保健的辖区,更大程度的物质剥夺和居住不稳定性与更多的房颤诊断相关,但消融治疗的可及性较低,这表明在房颤治疗的公平可及性方面存在显著的社会梯度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e03/11612362/da1f242654e0/ga1.jpg

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