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特刊:高负担低收入和中等收入国家产后出血防治的实施研究证据

Special Collection: Implementation Research Evidence for Prevention and Treatment of Postpartum Hemorrhage in High-Burden Low- and Middle-Income Countries.

作者信息

Salihu Hamisu M, Umar Amina A, Azuine Romuladus E

机构信息

Office of the Director General, Pfizer Kano Independent Research Center Trust, Kano, Nigeria.

Department of Community Health, Bayero University Teaching Hospital, Kano, Nigeria.

出版信息

Int J MCH AIDS. 2024 Sep 23;13(Suppl 1):S1-S3. doi: 10.25259/IJMA_35_2024. eCollection 2024 Sep.

DOI:10.25259/IJMA_35_2024
PMID:39629310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11583812/
Abstract

Postpartum hemorrhage (PPH), defined as a blood loss of 500 mL or more within 24 hours after birth, remains the leading cause of maternal mortality globally, accounting for over 20% of all maternal deaths. The burden of mortality from PPH is predominantly in low- and middle-income countries and demands coordinated accelerated efforts from the global maternal health community to meet the Sustainable Development 3 maternal health target by 2030. The International Journal of Maternal and Child Health and AIDS and the Concept Foundation are proud to present this Special Collection demonstrating the evidence for introducing heat-stable carbetocin and tranexamic acid, showcasing the feasibility and acceptability of their utilization for PPH prevention and management in resource-limited high-burden settings.

摘要

产后出血(PPH)定义为产后24小时内失血500毫升或更多,仍然是全球孕产妇死亡的主要原因,占所有孕产妇死亡的20%以上。产后出血导致的死亡负担主要集中在低收入和中等收入国家,需要全球孕产妇健康界共同加快协调努力,以实现到2030年的可持续发展目标3中的孕产妇健康目标。《国际母婴健康与艾滋病杂志》和概念基金会很荣幸推出本特刊,展示引入热稳定卡贝缩宫素和氨甲环酸的证据,展示它们在资源有限的高负担环境中用于预防和管理产后出血的可行性和可接受性。

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引用本文的文献

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Global, regional, and national trends in maternal hemorrhage, 1992-2021: a hierarchical cluster and age-period-cohort analysis of the Global Burden of Disease Study 2021 and projections to 2036.1992 - 2021年全球、区域和国家孕产妇出血趋势:全球疾病负担研究2021的分层聚类及年龄-时期-队列分析与至2036年的预测
BMC Public Health. 2025 Jul 24;25(1):2540. doi: 10.1186/s12889-025-23738-5.
2
Heat-Stable Carbetocin in the Management of Postpartum Haemorrhage in Low- and Middle-Income Countries: A Comprehensive Review of Clinical Evidence, Cost-Effectiveness, Implementation Challenges and Adoption Strategies.热稳定卡贝缩宫素用于低收入和中等收入国家产后出血的管理:临床证据、成本效益、实施挑战及采用策略的综合综述
Int J Womens Health. 2025 Jun 3;17:1615-1630. doi: 10.2147/IJWH.S515252. eCollection 2025.

本文引用的文献

1
Global causes of maternal death: a WHO systematic analysis.全球孕产妇死亡原因:世卫组织系统分析。
Lancet Glob Health. 2014 Jun;2(6):e323-33. doi: 10.1016/S2214-109X(14)70227-X. Epub 2014 May 5.