Alotaibi Shahad, Alshobaili Fahdah
Department of Family Medicine, King Saud University Medical City, King Khalid University Hospital, Riyadh, Saudi Arabia.
J Family Med Prim Care. 2024 Oct;13(10):4569-4574. doi: 10.4103/jfmpc.jfmpc_409_24. Epub 2024 Oct 18.
Recurrent pregnancy loss (RPL) is a common problem affecting many women. This study aimed to investigate the baseline characteristics of 400 women with RPL and to examine any differences in baseline characteristics of the recruited women with RPL throughout the years.
This study used retrospective data, which included the records of patients with RPL who visited King Khalid University Hospital's obstetric clinic between 2019 and 2022. The records of 400 patients who met the inclusion criteria were reviewed and analyzed.
The mean age of enrolled women was 36.5 ± 5.4 years, and the mean RPL was 3.8 ± 2.5. The study also revealed that there were significant statistical differences in obesity and vitamin D deficiency among women with RPL based on year ( = 0.013 and = 0.036, respectively), whereas no significant statistical differences were found between women with RPL in terms of age, parity, diabetes, hypothyroidism, hyperprolactinemia, antiphospholipid antibodies (APLs), uterine malformation, or consanguinity.
Advanced maternal age, number of previous miscarriages, parity, diabetes, hypothyroidism, APLs, uterine malformations, first-degree consanguinity, and vitamin D deficiency were found to be significant risk factors associated with RPL among women in Saudi Arabia.
复发性流产（RPL）是影响众多女性的常见问题。本研究旨在调查400例复发性流产女性的基线特征，并研究这些入选的复发性流产女性在不同年份的基线特征差异。
本研究采用回顾性数据，包括2019年至2022年间在哈立德国王大学医院产科门诊就诊的复发性流产患者的记录。对符合纳入标准的400例患者的记录进行了回顾和分析。
入选女性的平均年龄为36.5±5.4岁，平均复发性流产次数为3.8±2.5次。研究还显示，根据年份不同，复发性流产女性在肥胖和维生素D缺乏方面存在显著统计学差异（分别为=0.013和=0.036），而在年龄、产次、糖尿病、甲状腺功能减退、高泌乳素血症、抗磷脂抗体（APL）、子宫畸形或近亲结婚方面，复发性流产女性之间未发现显著统计学差异。
在沙特阿拉伯女性中，高龄产妇、既往流产次数、产次、糖尿病、甲状腺功能减退、抗磷脂抗体、子宫畸形、一级近亲结婚和维生素D缺乏被发现是与复发性流产相关的重要风险因素。
