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尾崎手术对血液学和生化指标的影响。

Effects of Ozaki procedure on hematological and biochemical parameters.

作者信息

Ozden Yasin, Peynirci Ferdi, Ozden Seyma, Senocak Mutlu, Sensoz Yavuz, Kayacioglu Ilyas

机构信息

Dr Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Department of Cardiovascular Surgery - İstanbul, Turkey.

Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Immunology and Allergy Clinic, Department of Chest Diseases - İstanbul, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2024 Dec 2;70(12):e20240944. doi: 10.1590/1806-9282.20240944. eCollection 2024.

DOI:10.1590/1806-9282.20240944
PMID:39630728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11639568/
Abstract

INTRODUCTION

The Ozaki procedure is an open-heart surgery technique used in aortic valve surgery. We investigated the effect of the Ozaki procedure on postoperative hematological and biochemical parameters as in other open-heart surgery applications.

METHODS

A total of 42 patients between December 2020 and December 2022 who underwent the Ozaki procedure were analyzed retrospectively. Patients without any comorbid cardiac pathology were included in the study. Preoperative 3rd day, postoperative 6th hour, postoperative 24th hour, postoperative 7th day, and postoperative 30th day hematological and biochemical parameters of 42 patients with screening results were examined.

RESULTS

Postoperative values were compared according to preoperative values. According to this, hematocrit and hemoglobin values were significantly lower at all times postoperatively. While white blood cells were found to be significantly higher until the postoperative 7th day, platelets were found to be significantly lower. The highest levels of creatine, blood urea, nitrogen, and aspartate aminotransferase were detected at the postoperative 24th hour, while the highest level for alanine aminotransferase was observed at the postoperative 7th day.

CONCLUSION

As with all open-heart surgery methods, the Ozaki procedure may cause some changes in hematological and biochemical parameters in the postoperative period. So, this situation is the same as in other open-heart surgery methods.

摘要

引言

尾崎手术是一种用于主动脉瓣手术的心脏直视手术技术。我们研究了尾崎手术对术后血液学和生化参数的影响,如同其他心脏直视手术应用一样。

方法

回顾性分析了2020年12月至2022年12月期间共42例行尾崎手术的患者。纳入研究的患者无任何合并心脏病变。对42例有筛查结果患者的术前第3天、术后第6小时、术后第24小时、术后第7天和术后第30天的血液学和生化参数进行了检查。

结果

根据术前值比较术后值。据此,术后所有时间点的血细胞比容和血红蛋白值均显著降低。虽然白细胞在术后第7天前显著升高,但血小板显著降低。术后第24小时检测到肌酸、血尿素、氮和天冬氨酸转氨酶的最高水平,而丙氨酸转氨酶的最高水平在术后第7天观察到。

结论

与所有心脏直视手术方法一样,尾崎手术在术后可能会导致血液学和生化参数出现一些变化。所以,这种情况与其他心脏直视手术方法相同。

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本文引用的文献

1
Clinical characteristics and risk factors of cardiac surgery associated-acute kidney injury progressed to chronic kidney disease in adults: A retrospective, observational cohort study.成人心脏手术相关急性肾损伤进展为慢性肾病的临床特征及危险因素:一项回顾性观察队列研究
Front Cardiovasc Med. 2023 Mar 8;10:1108538. doi: 10.3389/fcvm.2023.1108538. eCollection 2023.
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Understanding aortic valve repair through Ozaki procedure: A review of literature evidence.通过小崎手术理解主动脉瓣修复:文献证据综述
J Card Surg. 2022 Dec;37(12):5202-5206. doi: 10.1111/jocs.16846. Epub 2022 Sep 23.
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Aortic valve neocuspidization (the Ozaki procedure).主动脉瓣三叶化(Ozaki 手术)。
Multimed Man Cardiothorac Surg. 2021 Oct 12;2021. doi: 10.1510/mmcts.2021.060.
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ACUTE KIDNEY INJURY AFTER OPEN-HEART SURGERY PROCEDURES.心脏直视手术后的急性肾损伤。
Acta Clin Croat. 2021 Mar;60(1):120-126. doi: 10.20471/acc.2021.60.01.17.
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Acute Kidney Injury in Cardiac Surgery.心脏手术中的急性肾损伤。
Crit Care Clin. 2021 Apr;37(2):267-278. doi: 10.1016/j.ccc.2020.11.009. Epub 2021 Feb 13.
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Aortic Valve Neocuspidization with Glutaraldehyde-Treated Autologous Pericardium (Ozaki Procedure) - A Promising Surgical Technique.用戊二醛处理的自体心包进行主动脉瓣新瓣化(尾崎手术)——一种有前景的外科技术。
Braz J Cardiovasc Surg. 2019 Dec 1;34(5):610-614. doi: 10.21470/1678-9741-2019-0304.
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Anemia in Patients with Severe Aortic Stenosis.严重主动脉瓣狭窄患者的贫血。
Sci Rep. 2019 Feb 13;9(1):1924. doi: 10.1038/s41598-018-36066-z.
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Post-discharge kidney function is associated with subsequent ten-year renal progression risk among survivors of acute kidney injury.急性肾损伤幸存者出院后的肾功能与随后十年的肾脏进展风险相关。
Kidney Int. 2017 Aug;92(2):440-452. doi: 10.1016/j.kint.2017.02.019. Epub 2017 Apr 14.
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Cardiac surgery in patients with congenital heart disease is associated with acute kidney injury and the risk of chronic kidney disease.先天性心脏病患者心脏手术后易发生急性肾损伤和慢性肾脏病的风险。
Kidney Int. 2017 Sep;92(3):751-756. doi: 10.1016/j.kint.2017.02.021. Epub 2017 Apr 12.
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